Application effect of continuous blood purification in patients with severe sepsis and its impact on platelets
Objective To explore the treatment of severe sepsis in clinical practice,and the effectiveness and value of con-tinuous blood purification.Methods A total of 100 patients with severe sepsis from June 2018 to June 2021 admitted to the First People's Hospital of Nanning City were selected for the study.A random number table method was used to divide them into a control group(50 cases)and an experimental group(50 cases).Conventional treatment methods were applied to the control group,while the experimental group received continuous blood purification treatment.The total incidence of adverse reactions,clinical efficacy,platelet content,renal function indicators,and levels of inflammatory factors between two groups were compared.Results The total incidence of adverse reactions in the experimental group was lower than that in the control group,and the clinical efficacy was higher than that in the control group,and the platelet content was lower than that in the control group,and the differences were statistically significant(P＜0.05).The levels of creatinine,urea nitrogen,C-reactive protein(CRP),procalcitonin(PCT),and tumor necrosis factor-α(TNF-α)in the two groups before treatment showed no statistically significant differences(P＞0.05).After treatment,the creatinine,urea nitrogen,CRP,PCT,and TNF-α levels in the experimental group were lower than those in the control group,and the differences were statistically significant(P＜0.05).Conclusion Continuous blood purification therapy for patients with severe sepsis has a significant effect,which can significantly improve their renal function indicators and inflammatory factor levels.
万方数据
维普
