The evaluation value of perfusion index,lactic acid,ratio of central ve-nous-arterial carbon dioxide pressure difference to arterial-central ve-nous oxygen content difference for the prognosis in fluid resuscitation of sepsis
Objective To investigate the evaluation value of peripheral perfusion index(PI),blood lactic acid(Lac),ratio of central venous-arterial carbon dioxide pressure difference to arterial-central venous oxygen content difference(Pv-aCO2/Ca-vO2)for the prognosis in fluid resuscitation of sepsis.Methods A total of 82 patients with sepsis who were admitted to the People's Hospital of Jiangmen from July 2021 to December 2022 were selected as the study subjects.All patients were treated with fluid resuscitation through central venous catheter.According to the 28d prognosis,the patients were divided into a survival group(58 cases)and a death group(24 cases).The two groups were compared in terms of PI、Lac、Pv-a-CO2/Ca-vO2 at 6h after resuscitation.Receiver operating characteristic(ROC)curve analyses were performed to investigate the evaluation value of PI、Lac、Pv-aCO2/Ca-vO2.Results The PI of the survival group after 6 hours of resuscitation was higher than that of the death group,while Lac and Pv-aCO2/Ca-vO2 were lower than those of the death group,and the differences were statistically significant(P＜0.05).The sensitivity of PI,Lac and Pv-aCO2/Ca-vO2 for predicting poor prog-nosis of fluid resuscitation of sepsis were 66.67％,75.00％and 79.17％.The specificity were 87.93％,86.21％and 91.38％.The cut-off values were 0.350,4.625 and 1.720.The sensitivity and specificity of joint prediction were 87.50％and 94.83％(AUC=0.962).Conclusion The evaluation of PI,Lac and Pv-aCO2/Ca-vO2 is helpful for the prognosis of fluid resuscitation of sepsis.
万方数据
维普
