Clinical effect of drug balloon combined with spinous process balloon in the treatment of coronary bifurcation lesions
Objective To explore the clinical effect of drug balloon combined with spinous process balloon in the treatment of coronary bifurcation lesions.Methods A total of 50 patients with coronary bifurcation lesions admitted to Yichun Peo-ple's Hospital from October 2021 to October 2022 were selected as the study subjects.They were divided into a control group(25 cases)and an observation group(25 cases)according to random number table method.The control group received stent implantation combined with conventional balloon therapy,while the observation group received stent implantation combined with drug balloon therapy and spinous process balloon therapy.The treatment outcomes of coronary major branch(MB)and secondary branch(SB)(reference vessel diameter[RVD],minimum lumen diameter[MLD],diameter stenosis[DS]),late lumen loss(LLL)at 6 months after surgery,and differences in stent restenosis and major cardiovascular adverse events(MACE)at the bifurcation within 6 months after surgery were compared between the two groups.Results The MLD of MB in the observation group at 6 months after surgery was higher than that in the control group,with a statistically significant dif-ference(P＜0.05).The MLD of MB in the two groups of patients after surgery and 6 months after surgery were higher than those before surgery,while the DS of MB in the two groups were lower than those before surgery,with statistically significant differences(P＜0.05).The MLD of SB in the observation group at 6 months after surgery was higher than that in the control group,while the DS was lower than that in the control group,with statistically significant differences(P＜0.05).The MLD of SB in the two groups of patients after surgery and 6 months after surgery were higher than those before surgery,while the DS of SB in the two groups were lower than those before surgery,with statistically significant differences(P＜0.05).The LLL of MB and SB in the observation group at 6 months after surgery were lower than those in the control group,with statistically significant differences(P＜0.05).There was no statistically significant difference in the incidence of in-stent restenosis at the bifurcation within 6 months after surgery between the two groups of patients(P＞0.05).There was no statistically signifi-cant difference in the total incidence of MACE between the two groups of patients within 6 months after surgery(P＞0.05).Conclusion The application of drug balloon combined with spinous process balloon in the treatment of coronary bifurcation lesions can improve the treatment effect,improve the degree of stenosis of the lesion lumen,and reduce the incidence of LLL.
万方数据
维普
