首页|基于"病机-方-证-药"分析化肝煎治疗胃食管反流病的理论机制

基于"病机-方-证-药"分析化肝煎治疗胃食管反流病的理论机制

Based on"pathogenesis-formula-syndrome-medicine"to analyse the theoretical mechanism of Huagan Decoction in the treatment of gastroe-sophageal reflux disease

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胃食管反流病发病机制复杂,西药治疗通常很难得到满意的疗效.中医基于辨证论治对胃食管反流病发病的主要病机及病变过程产生的次要病机同时入手,治疗上依据主次确立基本治法,方从法出,用药精确,可有效缓解症状,还能极大降低药物不良反应和复发频率,为患者的预后及其生活质量提供重要保障.胃食管反流病的基本病机为肝胃郁热,胃气上逆,此为本,同时因人、因时、因病程不同,其他病机(燥、热、瘀、虚、痰)可为标实.本文拟从"病机-方-药-证"角度探讨化肝煎治疗胃食管反流病的理论机制.其主要治法是疏肝和胃、降逆清火,同时因人、因时、因病程长短,结合疏润结合、清化痰瘀、调养并举治法,贯穿于胃食管反流病的治疗过程中,以获良效.
The pathogenesis of gastroesophageal reflux disease is complex,and it is often difficult to obtain satisfactory cu-rative effect with western medicine.Traditional Chinese medicine based on syndrome differentiation and treatment,approach-es gastroesophageal reflux disease by addressing both the primary and secondary pathogenesis that contribute to its develop-ment.By establishing a hierarchy of treatment principles,precise herbal formulations,and medication strategies,traditional Chinese medicine effectively alleviates symptoms,significantly reduces adverse drug reactions,and lowers the recurrence rate,thereby providing crucial support for patient prognosis and quality of life.The basic pathogenesis of gastroesophageal reflux disease is liver and stomach stagnation heat,stomach Qi upward reversal,this is the basis,and due to different people,due to time,due to the course of disease,other pathogenesis(dryness,heat,stasis,deficiency,phlegm)can be the excess in superficiality.This paper aims to discuss the theoretical mechanism of Huagan Decoction in treating gastroesophageal reflux disease from the Angle of"pathogenesis-formula-syndrome-medicine".Its main treatment is to soothe the liver and stom-ach,reduce reverse and clear fire,and at the same time because of the person,because of the time,because of the length of the disease,combined with the combination of thinning and moistening,clearing phlegm and blood stasis,recuperation and treatment,throughout the treatment pro-cess of gastroesophageal reflux disease,or good effect.

Gastroesophageal reflux diseasePathogene-sis-formula-syndrome-medicineHuagan DecoctionThe-oretical mechanism

朱毅梁、邵岩峰、于莉、李婕、王庆莲

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福建中医药大学第一临床医学院,福建福州 350004

福建中医药大学附属第三人民医院脾胃病科,福建福州 350108

胃食管反流病 病机-方-证-药 化肝煎 理论机制

福建省临床重点专科建设项目福建中医药大学林平中医药传承工作室

闽卫医政函[2023]1163号闽中医[2023]56号

2024

中国当代医药
中国保健协会 当代创新(北京)医药科学研究院

中国当代医药

影响因子:1.215
ISSN:1674-4721
年,卷(期):2024.31(7)
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