Effect of Daglipzin on elderly patients with diabetes mellitus complicated with coronary heart disease and cardiac function
Objective To investigate the effect of Daglipzin on elderly patients with diabetes mellitus complicated with coronary heart disease and cardiac function.Methods A total of 80 elderly patients with diabetes mellitus combined with coronary heart disease admitted to First People's Hospital Fuzhou from July 2021 to December 2022 were selected as the study objects,and they were divided into observation group(40 cases)and control group(40 cases)according to random number table method.The observation group was treated with Dagliaglozin,and the control group was treated with Met-formin.The total effective rate,N-Terminal pro-brain natriuretic peptide(NT-proBNP),hypersensitive C-reactive protein(hs-CRP)and cardiac function of the two groups were compared.Results The total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P＜0.05).The level of NT-proBNP in the observation group was lower than that in the control group after treatment,and the difference was statistically signifi-cant(P＜0.05).The level of hs-CRP in observation group was lower than that in control group after treatment,and the dif-ference was statistically significant(P＜0.05).The left ventricular end-diastolic diameter(LVEDD)in the observation group was lower than that in the control group after treatment,and the left ventricular ejection fraction(LVEF),the diastolic early and late diastolic mitral valve opening ratio of the maximum blood flow velocity(E/A),the 6-minute walking distance in the observation group were higher than those in the control group,with statistical significances(P＜0.05).Conclusion Da-pagliflozin in the treatment of elderly patients with clinical diabetes mellitus and coronary heart disease,the evaluation re-sults of the intervention are better.After the implementation of treatment,the symptoms of the patient were improved,and the level of NT-proBNP and hs-CRP are reduced,the cardiac function level of the patient are improved to a certain extent,which is worthy of clinical application and promotion.
DapagliflozinDiabetes mellitus complicated with coronary heart diseaseElderly patientsCardiac function
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