首页|黄芪桂枝五物汤合雷火灸治疗2型糖尿病周围神经病变的临床效果

黄芪桂枝五物汤合雷火灸治疗2型糖尿病周围神经病变的临床效果

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目的 观察黄芪桂枝五物汤联合雷火灸治疗对2型糖尿病周围神经病变(DPN)患者的临床效果。方法 选取2021年11月至2023年1月江西中医药大学第二附属医院收治的70例2型DPN患者作为研究对象,采用随机数字表法分为对照组(35例)与治疗组(35例)。对照组口服甲钴胺片治疗,治疗组接受黄芪桂枝五物汤联合雷火灸治疗,两组患者均治疗8周。比较两组患者临床疗效、中医症候积分、C肽水平、血液流变学指标。结果 治疗组患者临床总有效率高于对照组,差异有统计学意义(P<0。05);治疗组患者治疗后手足麻木、肢体疼痛、肢体乏力等中医症候积分低于对照组,差异有统计学意义(P<0。05);两组患者治疗后空腹C肽(FC-P)、餐后2hC肽(2h C-P)水平均高于本组治疗前,且治疗组患者治疗后FC-P、2hC-P水平高于对照组,差异有统计学意义(P<0。05);治疗组患者治疗后血浆黏度、纤维蛋白原、红细胞比容水平均低于对照组,差异有统计学意义(P<0。05)。结论 黄芪桂枝五物汤联合雷火灸治疗能提高2型DPN患者临床疗效,减轻患者临床症状,同时提高C肽水平,并改善血液流变学。
Clinical effect of Huangqi Guizhi Wuwu Decoction combined with thun-der-fire moxibustion in the treatment of type 2 diabetic peripheral neu-ropathy
Objective To observe the clinical effect of Huangqi Guizhi Wuwu Decoction combined with thunder-fire moxi-bustion on type 2 diabetic peripheral neuropathy(DPN).Methods A total of 70 patients with type 2 DPN admitted to the Second Affiliated Hospital of Jiangxi University of CM from November 2021 to January 2023 were selected as the study ob-jects,and they were divided into control group(35 cases)and treatment group(35 cases)according to random number table method.The control group was treated with Mecobalamin Tablets,and the treatment group was treated with Huangqi Guizhi Wuwu Decoction combined with thunder-fire moxibustion.Two groups were treated for 8 weeks.The clinical efficacy,tradi-tional Chinese medicine syndrome score,C-peptide level and hemorheology indexes were compared between the two groups.Results The total effective rate of treatment group was higher than that of control group,the difference was statistically sig-nificant(P<0.05).The traditional Chinese medicine symptom scores such as hand and foot numbness,limb pain and limb weakness in the treatment group were lower than those in the control group after treatment,and the differences were statisti-cally significant(P<0.05).The levels of fasting C-peptide(FC-P)and 2-hour postprandial C-peptide(2 h C-P)in two groups after treatment were higher than those before treatment,and the levels of FC-P and 2 h C-P in treatment group were higher than those in control group,with statistical significances(P<0.05).After treatment,the plasma viscosity,fibrinogen and hematocrit in the treatment group were lower than those in the control group,and the differences were statistically sig-nificant(P<0.05).Conclusion Huangqi Guizhi Wuwu Decoction combined with thunder-fire moxibustion can improve the clinical effect,reduce the clinical symptoms,increase the level of C-peptide and improve the hemorheology of DPN patients.

Type 2 diabetic peripheral neuropathyHuangqi Guizhi Wuwu DecoctionThunder-fire moxibus-tionClinical efficacyC-peptide level

曾忠评、吴旭涛、章婷

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江西中医药大学第二附属医院内分泌代谢科,江西南昌 330012

2型糖尿病周围神经病变 黄芪桂枝五物汤 雷火灸治疗 临床疗效 C肽水平

江西省中医药管理局科技计划项目

2021A108

2024

中国当代医药
中国保健协会 当代创新(北京)医药科学研究院

中国当代医药

影响因子:1.215
ISSN:1674-4721
年,卷(期):2024.31(8)
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