Comparison of the effect of two kinds of automatic sedimentation meter on erythrocyte sedimentation rate
Objective To compare results of the determination of erythrocyte sedimentation rate(ESR)by Precil LBY-XC-40 automatic sedimentation rate analyzer(Brand A)and Alifax TEST1 automatic rapid sedimentation rate analyzer(Brand B),and evaluate the reliability of the measurement of ESR by different brands.Methods A total of 105 blood samples collected from the Second Affiliated Hospital of Guangzhou Medical University from January to February 2022 were selected to determine ESR by two kinds of automatic sedimentation system and Westergren method.The Westergren method as the gold standard,the correlation between the two kinds of automatic sedimentation meter and the Westergren method was compared,and the subgroup analysis was carried out.Results Brand A and B had good correlation with the measurement results of the Westergren method(r=0.890,0.902,P<0.05),and were in good agreement with the gold standard.There was no significant difference between the measurement results of Brand A and the Westergren method(P>0.05),while there was statistically significant difference between the measurement results of Brand B and the Wester-gren method(P<0.05).Further subgroup analysis of Brand B showed that when ESR<20 mm/h,the measurement result of Brand B was higher than that of Westergren method,and the difference was statistically significant(P<0.05).When ESR≥20 mm/h,there was no significant difference between the measurement results of Brand B and that of Westergren method(P>0.05).When hemoglobin ≤120 g/L,the detection result of Brand B was lower than that of Westergren method,the dif-ference was statistically significant(P<0.05);when hemoglobin>120 g/L,there was no statistically significant difference between Brand B and Westergren method(P>0.05).Conclusion The results of Brand A are similar to those of the Wester-gren method for ESR measurement,and can be used to replace the Westergren method for rapid ESR measurement in clinical practice.Brand B has a good correlation with the results of Westergren method for ESR measurement,but it needs to re-establish a matching reference interval to be more suitable for clinical ESR measurement.