Application of energy spectrum CT in the diagnosis of gastric cancer dif-ferentiation degree and metastatic lymph node
Objective To explore the application value of energy spectrum CT in the diagnosis of gastric cancer differentia-tion degree and metastatic lymph node.Methods A total of 60 patients diagnosed with gastric cancer by gastroscopy and pathological biopsy in Xinyu People's Hospital from January 2021 to April 2023 were selected as the study subjects.All the patients underwent energy spectrum CT examination and performed routine reconstruction and energy spectrum multi-pa-rameter and quantitative reconstruction.And all patients were grouped according to the degree of differentiation,including 18 cases in the poorly differentiated group,23 cases in the moderately differentiated group,and 19 cases in the well differ-entiated group.The differences in CT imaging signs and quantitative indicators of energy spectrum CT were compared among gastric cancer patients with different differentiation degrees and between patients with or without lymph node metastasis.Results The detection rates of local gastric wall thickening,gastric stenosis and serous layer roughness in the poorly differ-entiated group using conventional CT and spectral CT were higher than those in the moderately and well differentiated groups(P＜0.017).The detection rate of spectral CT was higher than that of conventional CT in the same group,and the dif-ference was statistically significant(P＜0.05).The iodine concentration,normalized iodine concentration(NIC),and the slope of spectral curve in different energy intervals in the poorly differentiated group were higher than those in the moderately and well differentiated groups,and the iodine concentration,NIC,and the slope of spectral curve in different energy intervals in the moderately differentiated group were higher than those in the well differentiated group,and the differences were sta-tistically significant(P＜0.05).The spectral CT results showed that the ratio of length to short diameter of lymph nodes,NIC,and CT value(hounsfield unit[HU])in the lymph node metastasis group were higher than those in the non-lymph node metastasis group,and the difference was statistically significant(P＜0.05).Conclusion Poorly differentiated gastric cancer often shows local gastric wall thickening,gastric cavity stenosis,and coarse serosa layer.There are significant differences in iodine concentration,NIC and other quantitative indicators of spectral CT in patients with different differentiation degrees and with or without lymph node metastasis.Therefore,spectral CT can provide valuable diagnosis for the differ-entiation degree of gastric cancer and the occurrence of metastatic lymph nodes.
Energy spectrum CTGastric cancerDiffer-entiation degreeMetastatic lymph node
万方数据
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