中国当代医药2024,Vol.31Issue(10) :31-34.

糖皮质激素联合桉柠蒎肠溶软胶囊治疗分泌性中耳炎的临床效果

Clinical effect of glucocorticoid combined with Eucalyptol,Limonene and Pinene Enteric Soft Capsules in the treatment of secretory otitis media

黄惠玲 杨凌鹏 朱友莲 古芬芳 罗冬梅 郭玉灵 陈岭蔚
中国当代医药2024,Vol.31Issue(10) :31-34.

糖皮质激素联合桉柠蒎肠溶软胶囊治疗分泌性中耳炎的临床效果

Clinical effect of glucocorticoid combined with Eucalyptol,Limonene and Pinene Enteric Soft Capsules in the treatment of secretory otitis media

黄惠玲 1杨凌鹏 1朱友莲 1古芬芳 1罗冬梅 1郭玉灵 1陈岭蔚1
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作者信息

  • 1. 江西省赣州市妇幼保健院耳鼻喉科,江西赣州 341000
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摘要

目的 探究糖皮质激素联合桉柠蒎肠溶软胶囊治疗分泌性中耳炎患者的临床效果.方法 选取2021年1月至2023年2月赣州市妇幼保健院的80例分泌性中耳炎患者作为研究对象,根据随机数表法分为对照组(40例)和观察组(40例).对照组采用糖皮质激素进行治疗,观察组采用糖皮质激素联合桉柠蒎肠溶软胶囊治疗.比较两组患者的治疗总有效率、鼓室压、语频气导听阈、症状体征积分及外周血T淋巴细胞亚群(CD3+、CD4+及CD8+).结果 观察组的分泌性中耳炎治疗总有效率高于对照组,差异有统计学意义(P<0.05).治疗前,两组患者的鼓室压、语频气导听阈、症状体征积分及外周血T淋巴细胞亚群比较,差异无统计学意义(P>0.05);治疗2周后,两组患者的鼓室压、语频气导听阈、症状体征积分均低于本组治疗前,且观察组的鼓室压、语频气导听阈、症状体征积分及CD8+均低于对照组,CD3+及CD4+均高于对照组,差异有统计学意义(P<0.05).结论 糖皮质激素联合桉柠蒎肠溶软胶囊治疗分泌性中耳炎患者的临床效果较好,可显著改善患者的相关症状体征及免疫状态,在分泌性中耳炎患者中的应用价值较高.

Abstract

Objective To investigate the clinical effect of glucocorticoid combined with Eucalyptol,Limonene and Pinene Enteric Soft Capsules in the treatment of secretory otitis media.Methods From January 2021 to February 2023,a total of 80 patients with secretory otitis media in Ganzhou Women and Children's Health Care Hospital were selected as the re-search objects.According to the random number table method,they were divided into the control group(40 cases)and the observation group(40 cases).The control group was treated with glucocorticoid,and the observation group was treated with glucocorticoid combined with Eucalyptol,Limonene and Pinene Enteric Soft Capsules.The total effective rate of treatment,tympanic pressure,speech frequency air conduction hearing threshold,symptom and sign scores and peripheral blood T lymphocyte subsets(CD3+,CD4+and CD8+)were compared between the two groups.Results The total effective rate of secre-tory otitis media in the observation group was higher than that in the control group,and the difference was statistically signif-icant(P<0.05).Before treatment,there were no statistically significant differences in tympanic pressure,speech frequency air conduction hearing threshold,symptom and sign scores and peripheral blood T lymphocyte subsets between the two groups(P>0.05).After 2 weeks of treatment,the tympanic pressure,speech frequency air conduction hearing threshold,symptom and sign scores of the two groups were lower than those before treatment,and the tympanic pressure,speech fre-quency air conduction hearing threshold,symptom and sign scores and CD8+of the observation group were lower than those of the control group,CD3+and CD4+were higher than those of the control group,and the differences were statistically signif-icant(P<0.05).Conclusion Glucocorticoid combined with Eucalyptol,Limonene and Pinene Enteric Soft Capsules has a good clinical effect in the treatment of patients with secretory otitis media,which can significantly improve the related symp-toms,signs and immune status of patients,and has a high application value in patients with secretory otitis media.

关键词

糖皮质激素/桉柠蒎肠溶软胶囊/分泌性中耳炎/临床效果/鼓室压/语频气导听阈

Key words

Glucocorticoid/Eucalyptol,Limonene and Pinene Enteric Soft Capsules/Secretory otitis media/Clinical effect/Tympanic pressure/Speech frequency air conduction hear-ing threshold

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基金项目

江西省卫生健康委科技项目(202212368)

江西省赣州市科技计划(GZ2021ZSF298)

出版年

2024
中国当代医药
中国保健协会 当代创新(北京)医药科学研究院

中国当代医药

影响因子:1.215
ISSN:1674-4721
参考文献量23
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