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四种信阳道地中草药挥发油杀菌效果的考察

Observation on sterilization effect of volatile oils from four kinds of Xinyang genuine Chinese herbs

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目的 考察藿香、苍术、野菊花及猫爪草四种信阳道地中草药挥发油的杀菌效果.方法 采用悬液定量杀菌试验方法,对藿香、苍术、野菊花、猫爪草单挥发油以及藿香与苍术、野菊花、猫爪草复配挥发油杀菌效果进行考察.结果 含质量分数2.0%及以上的藿香或野菊花挥发油溶液对悬液内金黄色葡萄球菌、大肠埃希菌、铜绿假单胞菌和白念珠菌这四种试验指标菌作用10 min,平均杀灭率均可达到99.9%以上.在含质量分数1.0%及以上复配挥发油的藿香与野菊花(1:1)组合物对悬液内四种试验菌作用10 min,平均杀灭率均达99.9%以上.结论 藿香、苍术、野菊花及猫爪草这四种信阳道地中草药挥发油对细菌和真菌具有较好的杀灭作用,藿香与野菊花组合物在降低挥发油量的同时,协同作用大大提高了复配挥发油的广谱杀菌活性,杀菌效果好,便于推广,但不同中草药挥发油对不同试验菌杀灭效果存在差异.
Objective To observe sterilization effect of volatile oils from four kinds of Xinyang genuine Chinese herbs(GCH)such as Agastache rugosa(Fisch.et Mey.)O.Ktze(A.rugosa),Atractylodes lancea(Thunb.)DC(A.lancea),Chrysan-themum indicum L(C.indicum L.)and Ranunculus ternatus Thunb.(R.ternatus).Methods Suspension quantitative ger-micidal test was used to observe sterilization effect of the single volatile oil and compound volatile oils from GCH such as Agastache rugosa(Fisch.et Mey.)O.Ktze(A.rugosa),Atractylodes lancea(Thunb.)DC(A.lancea),Chrysanthemum in-dicum L(C.indicum L.)and Ranunculus ternatus Thunb.(R.ternatus).Results The killing rates of Staphylococcus au-reus,Escherichia coli,Pseudomonas aeruginosa and Candida albicans exposed to solution containing ≥2.0% A.rugosa or C.indicum L.volatile oil for 10 minutes were>99.9%.The killing rates of four kinds of test bacteria exposed to solution containing ≥ 1.0% A.rugosa and C.indicum L.compound volatile oils for 10 minutes were>99.9%.Conclusion The volatile oils of four GCH from Xinyang such as A.rugosa,A.lancea,C.indicum L.,R.ternatus have good sterilization effect against bacteria and fungi.While reducing the amount of volatile oil,A.rugosa and C.indicum L.compound volatile oils have a synergistic efficacy,which greatly improves the broad-spectrum bactericidal activity with good sterilization effect for popularization.But the sterilization effect of volatile oils from different GCH on different test bacteria were different.

Genuine Chinese herbsVolatile oilCompoundSuspension quantitativeSterilization effect

王泽夏、高歌、刁婷婷、乔新荣、闫育涵、张秋会、李家兴、李静怡、朱乃亮

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信阳农林学院药学院,河南信阳 464000

道地中草药 挥发油 复配 悬液定量 杀菌效果

河南省高等学校大学生创新训练计划河南省信阳科技智库调研课题信阳农林学院科技创新团队建设项目

202311326006XYZK2302XNKJTD-009

2024

中国当代医药
中国保健协会 当代创新(北京)医药科学研究院

中国当代医药

影响因子:1.215
ISSN:1674-4721
年,卷(期):2024.31(11)
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