首页|两种商品化培养液的辅助生殖结局比较

两种商品化培养液的辅助生殖结局比较

Comparison of assisted reproductive outcomes between two commercial cultures

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目的 探讨不同商品化培养液对体外培养胚胎的临床结局和出生结局的影响.方法 回顾性分析2020年1月至2021年10月符合纳入标准的1 540个取卵周期的患者临床资料,根据使用不同商品化培养液进行分组,其中Vitrolife组有831个周期,Cook组有709个周期,比较分析两组的体外胚胎发育情况和临床结局.结果 Cook组的D3优质胚胎率(69.63%vs.67.54%)、囊胚形成率(53.47%vs.49.01%)、可利用囊胚形成率(46.72%vs.42.70%)和D5可利用囊胚形成率(35.03%vs.30.32%)均高于Vitrolife组,差异有统计学意义(P<0.05);两组之间的其余体外胚胎发育情况、临床结局和新生儿出生结局比较,差异无统计学意义(P>0.05).结论 本研究提示在常规体外受精和胚胎移植周期中,培养液可能影响体外培养胚胎的优质胚胎和囊胚的形成.
Objective To investigate the effect of different commercial culture media on the clinical and birth outcomes of in vitro cultured embryos.Methods The clinical data of 1 540 oocyte retrieval cycles meeting the inclusion criteria from Jan-uary 2020 to October 2021 were analyzed retrospectively according to the use of different commercial culture media,including 831 cycles in Vitrolife group and 709 cycles in Cook group to compare the in vitro embryo development and clinical outcomes of the two groups.Results The D3 high-quality embryo rate(69.63%vs.67.54%),rate of blastocyst for-mation(53.47%vs.49.01%),rate of blastocyst formation can be utilized(46.72%vs.42.70%)and D5 rate of blastocyst for-mation can be utilized(35.03%vs.30.32%)in the Cook group were higher than those in the Vitrolife group,the differences were statistically significant(P<0.05).Conclusion Culture media may affect the formation of high-quality embryos and blastocysts during in vitro insemination and embryo transfer cycles.

Culture mediumHigh-quality embryo rateBlastocyst formation rateRate of blastocyst formation can be utilized

林运鸿、黄鹏宇、史航、杜生荣、孙艳、郑备红

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福建省妇幼保健院生殖医学中心,福建福州 350001

培养液 优质胚胎率 囊胚形成率 可利用囊胚形成率

2024

中国当代医药
中国保健协会 当代创新(北京)医药科学研究院

中国当代医药

影响因子:1.215
ISSN:1674-4721
年,卷(期):2024.31(11)
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