Objective To explore the clinical effect of postoperative synchronous adjuvant chemordiotherapy for breast can-cer patients.Methods A total of sixty patients with breast cancer admitted to Heze Peony People's Hospital from February 2020 to August 2022 were selected as the study objects.According to the random number table method,they were divided into the reference group(30 cases)and the study group(30 cases).The reference group was treated with postoperative adju-vant sequential therapy,while the study group was treated with postoperative adjuvant chemoradiotherapy.The rate of distant metastasis,local recurrence rate,disease-free progression rate,duration of radiotherapy and chemotherapy,initiation time of radiotherapy,and total incidence of adverse reactions(gastrointestinal reactions,leukopenia)were compared between the two groups.Results There were no significant differences in the rate of distant metastasis,local recurrence and no disease pro-gression in the study group compared with the reference group(P＞0.05).The whole treatment time of radiotherapy and chemotherapy in the study group was shorter than that in the reference group,and the difference was statistically significant(P＜0.05).The total incidence of adverse reactions(gastrointestinal reactions,leukopenia)in the study group was compared with that in the reference group,and the difference was not statistically significant(P＞0.05).The total effective rate in the study group was higher than that in the reference group,and the difference was statistically significant(P＜0.05).Conclu-sion Clinical use of synchronous adjuvant chemoradiotherapy for postoperative treatment of breast cancer patients can effec-tively shorten the whole treatment time of chemoradiotherapy and the start time of radiotherapy compared with conventional sequential therapy,and there are no significant differences in the rate of distant metastasis,local recurrence rate,dis-ease-free progression rate and total incidence of adverse reactions.The value of simultaneous adjuvant chemoradiotherapy in postoperative treatment of breast cancer patients is further explained.
关键词
乳腺癌/术后同步辅助放化疗/序贯治疗/远处转移率/局部复发率/无疾病进展率/不良反应
Key words
Breast cancer/Postoperative synchronous adjuvant chemoradiotherapy/Sequential treatment/Distant metasta-sis rate/Local recurrence rate/Rate of no disease progression/Adverse reaction
维普
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