中国当代医药2024,Vol.31Issue(14) :88-91.

苏合香丸联合丁苯酞氯化钠治疗脑梗死的临床效果

Clinical effect of Suhexiang Pills combined with Sodium Butylphthalide Chloride in the treatment of cerebral infarction

谢晨璐 钟立伟 吴漫 杨华彪 孔越
中国当代医药2024,Vol.31Issue(14) :88-91.

苏合香丸联合丁苯酞氯化钠治疗脑梗死的临床效果

Clinical effect of Suhexiang Pills combined with Sodium Butylphthalide Chloride in the treatment of cerebral infarction

谢晨璐 1钟立伟 2吴漫 1杨华彪 2孔越1
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作者信息

  • 1. 江西省九江市中医医院药剂科,江西九江,332000
  • 2. 江西省九江市中医医院脑病科,江西九江,332000
  • 折叠

摘要

目的 探讨苏合香丸联合丁苯酞氯化钠改善脑梗死患者预后的效果.方法 选取2021年3月至2023年3月九江市中医医院收治的100例急性脑梗死(ACI)患者,按随机数字表法将分为对照组(50例)和治疗组(50例).对照组患者采用阿司匹林或氯吡格雷治疗,治疗组患者加用苏合香丸、丁苯酞氯化钠注射液治疗,共治疗14 d.比较两组患者的临床疗效、症状改善情况、凝血功能、炎症因子水平、神经功能、并发症及安全性.结果 治疗组总有效率高于对照组,两组治疗后症状评分、美国国立卫生研究院卒中量表(NIHSS)及D-二聚体(D-D)、纤维蛋白原(FIB)、白介素-6(IL-6)、白介素-8(IL-8)水平均低于本组治疗前,且治疗组低于对照组(P<0.05);治疗组并发症总发生率低于对照组(P<0.05);两组不良反应比较,差异无统计学意义(P>0.05).结论 苏合香丸联合丁苯酞氯化钠治疗ACI的整体效果确切,可发挥抗凝、减轻炎症反应、促进神经功能恢复等作用,且并发症少,安全性好,值得推广.

Abstract

Objective To explore the effect of Suhexiang Pills combined with Sodium Butylphthalide Chloride on improving the prognosis of patients with cerebral infarction.Methods A total of 100 patients with acute cerebral infarction(ACI)ad-mitted to Jiujiang Traditional Chinese Medicine Hospital from March 2021 to March 2023 were divided into control group(50 cases)and a treatment group(50 cases)according to the random number table method.The control group patients were treated with aspirin or clopidogrel,while the treatment group patients were treated with Suhexiang Pills and Sodium Butylphthalide Chloride Injection for a total of 14 days.The clinical efficacy,symptom improvement,coagulation function,inflammatory cytokine levels,neurological function,complications,and safety were compared between two groups of patients.Results The total effective rate of the treatment group was higher than that of the control group,and the symptom score,Na-tional Institute of Health stroke scale(NIHSS),D-dimer(D-D),fibrinogen(FIB),interleukin-6(IL-6),and interleukin-8(IL-8)levels of the two groups after treatment were all lower than those before treatment in the same group,and these index-es the treatment group were lower than the control group,and the differences were statistically significant(P<0.05).The to-tal incidence of complications in the treatment group was lower than that in the control group,and the difference was statisti-cally significant(P<0.05).There was no statistically significant difference in the adverse reactions between the two groups(P>0.05).Conclusion The overall effect of Suhexiang Pills combined with Sodium Butylphthalide Chloride in the treatment of ACI is definite,which can exert anticoagulation,reduce inflammatory reactions,promote neurological function recovery,and has fewer complications and good safety.It is worth promoting.

关键词

脑梗死/苏合香丸/丁苯酞氯化钠/凝血功能/炎症因子/神经功能/并发症/安全性

Key words

Cerebral infarction/Suhexiang Pills/Sodium Butylphthalide Chloride/Coagulation function/Inflammatory fac-tors/Neurological function/Complications/Security

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出版年

2024
中国当代医药
中国保健协会 当代创新(北京)医药科学研究院

中国当代医药

影响因子:1.215
ISSN:1674-4721
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