Objective To analyze the value of sequential recanalization interventional therapy for senile acute myocardial infarction.Methods A total of 86 elderly patients with acute myocardial infarction admitted to Shandong Guoxin Health Care Group Zaozhuang Central Hospital from August 2022 to August 2023 were selected as the study objects.According to the order of admission,they were divided into conventional group(43 cases admitted first)and sequential group(43 cases ad-mitted later).The conventional group received routine interventional treatment,and the sequential group received sequential recanalization intervention therapy.Electrocardiogram indexes,cardiac function,biochemical indexes and incidence of QRS burst were compared between the two groups.Results Before intervention,there were no significant differences in electro-cardiogram indexes between the two groups(P＞0.05).After intervention,the electrocardiogram indexes of the two groups were higher than those before intervention,and the electrocardiogram indexes of the sequential group were higher than those of the conventional group,with statistical significances(P＜0.05).Before intervention,there were no significant differences in cardiac function indexes between the two groups(P＞0.05).After intervention,the left ventricular ejection fraction(LVEF)and left ventricular end-systolic diameter(LVESD)of the two groups were higher than those before intervention,and the left ventricular end-diastolic diameter(LVEDD)of the two groups were lower than those before intervention,and the LVEF and LVESD of the sequential group were higher than those of the conventional group,and the LVEDD of the sequen-tial group was lower than that of the conventional group,with statistical significances(P＜0.05).Before intervention,there were no significant differences in biochemical indexes between the two groups(P＞0.05).After intervention,the levels of matrix metalloproteinase 9(MMP-9)and cystatin C in two groups were lower than those before intervention,and the levels of MMP-9 and cystatin C in the sequential group were lower than those in the conventional group,with statistical sig-nificances(P＜0.05).There was no significant difference in the incidence of QRS burst before intervention between the two groups(P＞0.05).The incidence of QRS burst after intervention in sequential group was lower than that in conventional group,and the difference was statistically significant(P＜0.05).Conclusion Sequential recanalization interventional therapy can regulate MMP-9,restore myocardial blood flow,improve cardiac function,effectively reduce QRS burst events,and im-prove the prognosis of senile acute myocardial infarction.
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