首页|老年2型糖尿病合并冠心病患者心脏不良事件的危险因素分析

老年2型糖尿病合并冠心病患者心脏不良事件的危险因素分析

Analysis of risk factors of adverse cardiac events in elderly patients with type 2 diabetes mellitus complicated with coronary heart disease

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原文链接
  • 国家科技期刊平台
  • NETL
  • NSTL
  • 万方数据
目的 探讨老年2型糖尿病合并冠心病患者的心脏不良事件发生风险及其危险因素.方法 采用简单随机抽样法选取2019年1月至2022年12月上饶市人民医院收治的182例老年2型糖尿病合并冠心病患者为研究对象,按照有无发生心脏不良事件分为发生组(28例)与未发生组(154例).对症治疗后出院随访90 d,记录患者心脏不良事件发生风险,收集并比较两组患者的一般临床资料、实验室指标、超声心电图(ECG)指标.采用多因素logistic回归分析发生心脏不良事件的危险因素.结果 随访90 d,182例2型糖尿病合并冠心病患者中,28例患者发生心脏不良事件,发生率为15.38％;不同心脏不良事件发生组左主干病变、糖化血红蛋白(HbA1c)、左房前后径(LAD)、左室射血分数(LVEF)、美国纽约心脏病学会(NYHA)心功能分级比较,差异有统计学意义(P＜0.05);多因素 logistic 回归分析结果显示,左主干病变(β=2.321,OR=10.186,95％CI:2.464～42.100)、HbA1c(β=2.482,OR=11.968,95％CI:2.436～58.763)、LAD(β=3.183,OR=24.119,95％CI:6.989～83.239)、心功能分级(β=1.287,OR=3.622,95％CI:1.775～7.392)、C 型病变(β=3.254,OR=25.894,95％CI:7.285～92.303)为 2 型糖尿病合并冠心病患者心脏不良事件发生的危险因素.结论 左主干病变、HbA1c、LAD、LVEF、心功能分级、C型病变为2型糖尿病合并冠心病患者心脏不良事件发生的危险因素.
Objective To explore the risk and risk factors of adverse cardiac events in elderly patients with type 2 diabetes and coronary heart disease.Methods A total of 182 elderly patients with type 2 diabetes complicated with coronary heart disease admitted to Shangrao People's Hospital from January 2019 to December 2022 were selected by simple random sam-pling as the study objects.They were divided into occurrence group(28 cases)and un-occurred group(154 cases)according to the occurrence of adverse cardiac events.After symptomatic treatment,the patients were followed up for 90 days after dis-charge to record the risk of adverse cardiac events,and the general clinical data,laboratory indicators,and ultrasonic elec-trocardiogram(ECG)indicators of the patients were collected and compared in the two groups.The multiple logistic regres-sion analysis was used to identify risk factors for adverse cardiac events.Results After 90 days of follow-up,28 of 182 pa-tients with type 2 diabetes combined with coronary heart disease had adverse cardiac events,and the incidence rate was 15.38％,there were significant differences(P＜0.05)in the incidence of left main coronary artery disease,glycated hemoglobin(HbA1c),language acquisition device(LAD),left ventricular ejection fraction(LVEF),and New York Heart As-sociation(NYHA)cardiac function grading among different groups of adverse cardiac events.The results of multiple logistic factor analysis showed that the left main trunk lesion(β=2.321,OR=10.186,95％CI:2.464-42.100),HbA1c(β=2.482,OR=11.968,95％CI:2.436-58.763),LAD(β=3.183,OR=24.119,95％CI:6.989-83.239),cardiac function classification(β=1.287,OR=3.622,95％CI:1.775-7.392),type C lesions(β=3.254,OR=25.894,95％CI:7.285-92.303)were the risk factors for adverse cardiac events in patients with type 2 diabetes and coronary heart disease.Conclusion Left main artery disease,HbA1c,LAD,LVEF,cardiac function classification,and type C disease are the risk factors for adverse cardiac events in patients with type 2 diabetes combined with coronary heart disease.

Type 2 diabetesCoronary heart diseaseAdverse cardiac eventsRisk factors

余鸿博、廖玲、汪小丽

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江西省上饶市人民医院全科医学科,江西上饶 334000

2型糖尿病 冠心病 心脏不良事件 危险因素

2024

中国当代医药
中国保健协会 当代创新（北京）医药科学研究院

中国当代医药

影响因子：1.215
ISSN：1674-4721
年,卷(期)：2024.31(18)