中国当代医药2024,Vol.31Issue(19) :95-100.

天麻降压胶囊治疗H型高血压肝火亢盛证的临床效果及对同型半胱氨酸、超敏C反应蛋白的影响

Clinical effect of Tianma Jiangya Capsules in the treatment of H-type hy-pertension(hyperactivity of liver fire syndrome)and its influence on ho-mocysteine and hypersensitive C-reactive protein

曹宝国 刘惠娟 樊红波 陈圆圆 秦少华
中国当代医药2024,Vol.31Issue(19) :95-100.

天麻降压胶囊治疗H型高血压肝火亢盛证的临床效果及对同型半胱氨酸、超敏C反应蛋白的影响

Clinical effect of Tianma Jiangya Capsules in the treatment of H-type hy-pertension(hyperactivity of liver fire syndrome)and its influence on ho-mocysteine and hypersensitive C-reactive protein

曹宝国 1刘惠娟 2樊红波 2陈圆圆 3秦少华4
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作者信息

  • 1. 甘肃省天水市中西医结合医院心内科,甘肃天水 741000
  • 2. 甘肃省天水市中医医院药剂科,甘肃天水 741000
  • 3. 甘肃省天水市中医医院心血管科,甘肃天水 741000
  • 4. 甘肃省天水市中医医院医务科,甘肃天水 741000
  • 折叠

摘要

目的 观察天麻降压胶囊治疗H型高血压(肝火亢盛证)的临床效果及对同型半胱氨酸(Hcy)、超敏C反应蛋白(hs-CRP)的影响.方法 选取2021年5月至2022年12月天水市中医医院就诊的165例轻、中度H型高血压(肝火亢盛证)患者作为研究对象,按照随机数字表法将其分为对照组(83例)和治疗组(82例).对照组予以马来酸依那普利叶酸片治疗,治疗组在对照组基础上加服天麻降压胶囊治疗,两组均治疗3个月.比较治疗前后两组患者的收缩压、舒张压、Hcy、hs-CRP水平及中医证候积分的情况,并判断血压疗效及中医疗效.结果 治疗后,两组患者的收缩压与舒张压均低于本组治疗前,且治疗组的收缩压与舒张压均低于对照组,差异有统计学意义(P<0.05);治疗组的血压总有效率(97.56%)高于对照组(86.75%),差异有统计学意义(P<0.05).治疗后,两组患者的Hcy、hs-CRP水平及中医证候总积分均低于本组治疗前,且治疗组的Hcy、hs-CRP水平及中医证候总积分均低于对照组,差异有统计学意义(P<0.05);治疗组的中医治疗总有效率(85.37%)高于对照组(73.49%),差异有统计学意义(P<0.05).结论 天麻降压胶囊治疗H型高血压(肝火亢盛证)具有较好的临床疗效,可显著改善患者症状,降低Hcy、hs-CRP水平,值得进一步推广应用.

Abstract

Objective To observe the clinical effect of Tianma Jiangya Capsules in the treatment of H-type hypertension(hyperactivity of liver fire syndrome)and its effect on homocysteine and hypersensitive C-reactive protein.Methods A total of 165 patients with mild to moderate H-type hypertension(hyperactivity of liver fire syndrome)who visited Traditional Chi-nese Medicine Hospital of Tianshui City from May 2021 to December 2022 were selected as the research subjects.They were divided into control group(83 cases)and treatment group(82 cases)according to the random number table method.The control group was given Enalapril Maleate and Folic Acid Tablets,and the treatment group was given Tianma Jiangya Cap-sules on basis of the control group,both groups were treated for 3 months.The systolic blood pressure,diastolic blood pres-sure,blood Hcy,hs-CRP levels,and traditional Chinese medicine syndrome scores of the two groups before and after treat-ment were compared,and the efficacy of blood pressure and traditional Chinese Medicine were judged.Results After treat-ment,the systolic blood pressure and diastolic blood pressure of the two groups were lower than those before treatment,and the systolic blood pressure and diastolic blood pressure of the treatment group were lower than those of the control group,and the differences were statistically significant(P<0.05).The total effective rate of blood pressure in the treatment group(97.56%)was higher than that of the control group(86.75%),and the difference was statistically significant(P<0.05).After treatment,the Hcy,hs-CRP levels and traditional Chinese medicine syndrome total scores of the two groups were lower than those before treatment,and the Hcy,hs-CRP levels and traditional Chinese medicine syndrome total scores of the treatment group were lower than those of the control group,and the differences were statistically significant(P<0.05).The total effective rate of traditional Chinese medicine in the treatment group(85.37%)was higher than that of the control group(73.49%),and the difference was statistically significant(P<0.05).Conclusion Tianma Jiangya Capsules has a good clini-cal efficacy in the treatment of type H hypertension(hyperactivity of liver fire syndrome),which can significantly improve the symptoms of patients,reduce the levels of blood Hcy and hs-CRP,and is worthy of further promotion and application.

关键词

H型高血压/肝火亢盛证/天麻降压胶囊/同型半胱氨酸/超敏C反应蛋白

Key words

H-Type hypertension/Syndrome of hyperactivity of liver fire/Tianma Jiangya Capsules/Homocysteine/Hy-persensitivity C-reactive protein

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基金项目

甘肃省科技计划(技术创新引导计划)项目(21CX6FE176)

出版年

2024
中国当代医药
中国保健协会 当代创新(北京)医药科学研究院

中国当代医药

影响因子:1.215
ISSN:1674-4721
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