Progress of clinical characteristics,pathogenesis and treatment of obstruc-tive sleep apnea hypopnea syndrome complicated with arrhythmias
With the increasing incidence of obstructive sleep apnea hypopnea syndrome(OSAHS)complicated with ar-rhythmia year by year,its impact on patients'life safety and quality of life is becoming increasingly serious,and it has be-come an important public health challenge worldwide.This article reviews the clinical characteristics,pathogenesis and treatment progress of OSAHS complicated with arrhythmia,aiming to attract the attention of relevant practitioners and pro-vide help for the clinical diagnosis and treatment of this disease.OSAHS may be associated with a variety of arrhythmia types,and most of them occur at night.The pathogenesis of OSAHS combined with arrhythmia involves several interrelated physiological processes.The main mechanism of its occurrence is intermittent hypoxia and hypercapnia usually accompanied by OSAHS,which cause autonomic nervous dysfunction and the change of negative pressure in the chest,and then lead to myocardial ischemia,oxidative stress,inflammatory response and endothelial damage,and even change the heart structure and function.Therefore,the treatment of OSAHS combined with arrhythmia requires a comprehensive medical approach aimed at improving the management of OSAHS and dealing with the arrhythmia itself.
万方数据
维普
