Application of ratio of optic nerve sheath diameter to transverse diameter of eyeball in monitoring intracranial pressure in patients with cerebral edema
Objective To investigate the value of the ratio of optic nerve sheath diameter(ONSD)to eyeball transverse di-ameter(ETD)in monitoring intracranial pressure(ICP)in patients with cerebral edema.Methods Clinical data of 50 pa-tients with cerebral edema admitted to Zhangzhou Municipal Hospital of Fujian Province from January 2022 to October 2023 were retrospectively analyzed.ONSD and ETD were measured by ultrasound in all patients,and their ratios were calculated.According to the invasive ICP monitoring values,the patients were divided into the increased ICP group(n=31,≥ 200 mmHg)and the normal ICP group(n=19,80-200 mmHg).Univariate and multivariate Logistic regression were used to ana-lyze the influencing factors of increased ICP in patients with cerebral edema.ROC curve was used to analyze the predictive value of ONSD,ETD and ONSD/ETD on ICP increase in patients with brain edema,and Pearson correlation was used to an-alyze the relationship between ONSD,ONSD/ETD and ICP increase in patients with brain edema.Results Univariate analy-sis showed that there were significant differences in ONSD,ONSD/ETD ratio,GCS score,NIHSS score and APACHE Ⅱscore between the two groups(P＜0.05).Multivariate logistic regression analysis showed that ONSD(β=0.778,OR=2.177,95％CI=1.275-3.718),ONSD/ETD ratio(β=0.826,OR=2.284,95％CI=1.218-4.285)were independent risk factor for in-creased ICP in patients with cerebral edema,and the difference was statistically significant(P＜0.05).ROC curve results showed that the ratio of ONSD/ETD predicted the AUC,specificity and sensitivity of ICP increase in patients with cerebral edema were 0.952,96.80％and 78.90％,respec-tively,and the prediction efficiency was higher than ONSD,the difference was statistically significant(P＜0.05).ONSD/ETD ratio was positively correlated with ICP,and the difference was statistically significant(r=0.523,P＜0.001).Conclusion The ratio of ONSD/ETD is a risk factor for the increase of ICP in patients with cerebral edema,and has a good predictive value for the increase of ICP in patients with cerebral edema.
Cerebral edemaIntracranial pressureOptic nerve sheath diameter to eyeball transverse diameter ratioPre-dictive value
维普
万方数据
