首页|丹参注射液对肺尘埃沉着病合并肺心病患者的临床疗效、右心功能及血气分析的影响

丹参注射液对肺尘埃沉着病合并肺心病患者的临床疗效、右心功能及血气分析的影响

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目的 探讨丹参注射液对肺尘埃沉着病合并肺心病患者的临床效果。方法 选取 2020 年 1 月至 2021 年 12月赣州市第五人民医院收治的 60 例肺尘埃沉着病合并肺心病患者作为研究对象,按照随机数字表法分为常规组(n=30)与丹参组(n=30)。常规组采用常规对症治疗,丹参组在常规组的基础上加用丹参注射液进行治疗,两组患者均连续治疗两周。分别于治疗前后对两组患者进行心脏彩色多普勒超声检查,比较两组患者右心腔的大小和右心室Tei指数,并比较两组患者的临床疗效和血气分析。结果 丹参组的临床治疗总有效率、动脉血氧分压和血氧饱和度高于常规组,丹参组的右心腔大小和右心室Tei指数低于常规组,丹参组的动脉血二氧化碳分压低于常规组,差异有统计学意义(P<0。05)。结论 丹参注射液能够有效改善肺尘埃沉着病合并肺心病患者的临床症状、血气指标及右心功能。
Effect of Danshen Injection on the clinical efficacy,right heart function and blood gas analysis of pneumoconiosis complicated with pulmonary heart disease
Objective To investigate the clinical effect of Danshen Injection on pneumoconiosis complicated with pul-monary heart disease.Methods A total of 60 patients with pneumoconiosis combined with pulmonary heart disease admitted to the Fifth People's Hospital of Ganzhou from January 2020 to December 2021 were selected as the study objects,and they were divided into the conventional group(n=30)and the Danshen group(n=30)according to random number table method.The conventional group was treated with conventional symptomatic treatment,and the Danshen group was treated with Dan-shen Injection on the basis of the conventional group.Both the two groups were treated continuously for two weeks.Cardiac color Doppler ultrasound was performed before and after treatment to compare the size of the right heart cavity and the Tei index of the right ventricle between the two groups,the clinical efficacy and blood gas analysis were compared between the two groups.Results The total effective rate,partial arterial oxygen pressure,blood oxygen saturation percentage in Danshen group were higher than those in the conventional group,right ventricular cavity size and right ventricular Tei index in Dan-shen group were lower than those in the conventional group,and the partial pressure of carbon dioxide in arterial blood in the Danshen group was lower than that in the conventional group,the differences were statistically significant(P<0.05).Con-clusion Danshen injection can effectively improve the clinical symptoms,blood gas index and right heart function in patients with pneumoconiosis complicated with pulmonary heart disease.

Danshen InjectionPneumoconiosis complicated with pulmonary heart diseaseClinical symptomBlood gas indexRight heart functionColor Doppler ultrasound

卢致婷、刘辉、龚享文、崔开旺、赖秋香、潘艳群、万丽兰、谢美华

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江西省赣州市第五人民医院功能科,江西赣州 341000

江西省赣州市第五人民医院呼吸与危重症医学科,江西赣州 341000

丹参注射液 肺尘埃沉着病合并肺心病 临床效果 血气指标 右心功能 彩色多普勒超声

2024

中国当代医药
中国保健协会 当代创新(北京)医药科学研究院

中国当代医药

影响因子:1.215
ISSN:1674-4721
年,卷(期):2024.31(25)