Research progress on anti-depression effect of Chaihu Jia Longgu Muli Decoction
Depression is an important mental illness which seriously affects people's physical and mental health.Nowadays,it is mainly treated with Western medicine,such as Fluoxetine,Sertraline,Paroxetine,Fluvoxamine,etc.These drugs are se-lective 5-hydroxytryptamine reuptake inhibitors,although they can temporarily play the role of antidepressant,but the long-term use will lead to a series of adverse reactions,such as anxiety,nausea and vomiting,dizziness and headache,and so on,and the efficacy of long-term use is unstable.Chaihu Jia Longgu Muli Decoction is taken from ZHANG Zhongjing's Treatise on Febrile Cold and Shaoyang.The main ingredients of the original recipe are bupleurum,keel,oyster,pinellia,ginseng,scutellaria,minium and so on.With the study of modern Chinese medicine,the minium in the original prescription was replaced by magnet and ochre.Chaihu Jia Longgu Muli Decoction can regulate neurotransmitter,central nervous cell function and immune state,so as to achieve the purpose of treating depression.Chaihu Jia Longgu Muli Decoction has the function of clearing Shaoyang qi and calming the mind.The prescription has multi-target and multifaceted antidepressant effect.In the clinical treatment of patients with depression,Chaihu Jia Longgu Muli Decoction has played an important role.This study reviewed the antidepressant effects of Chaihu Jia Longgu Muli Decoction.