Research progress in novel biomarkers of sepsis-associated acute kidney injury
Sepsis is a systemic inflammatory response syndrome that causes multiple organ dysfunction due to the body's response to infection,kidney is one of the most affected organs.The incidence of sepsis combined with acute kidney injury has been high worldwide,and due to its poor prognosis,it is a major difficulty in emergency medicine and intensive care medicine.Therefore,early diagnosis and early intervention in the clinical treatment of sepsis-associated acute kidney injury(SA-AKI)are crucial.The current diagnostic criteria for acute kidney injury that rely on urine volume and serum creatinine have certain limitations,thus delaying early diagnosis and effective treatment.In this paper,we summarize the latest progress of SA-AKI biomarker research,aiming to fill the gap in the early diagnosis of SA-AKI.