Objective To investigate the clinical value of neurally adjusted ventilatory assist(NAVA)in the treatment of neonatal acute respiratory distress syndrome(NARDS).Methods A total of 60 children with NARDS in Jiangxi Provincial Children's Hospital from October 2019 to October 2023 were selected as the research objects.According to the random number table method,they were divided into the control group and the observation group(30 cases in each group).The con-trol group was ventilated with synchro-nized intermittent mandatory ventilation(SIMV)mode,and the observation group was ventilated with NAVA mode,each grope ventilated for 2 h.Blood gas indexes,respiratory mechanics parameters,inspiratory trigger delay time and complication rate were compared between the two groups.Results After treatment,there were no sig-nificant differences in arterial partial pressure of oxygen(PaO2),partial pressure of carbon dioxide(PaCO2),oxygen saturation of blood(SaO2)and oxygenation index(PaO2/FiO2)between the two groups(P＞0.05).After treatment,the peak inspiratory pressure(PIP),spontaneous respiratory rate(RR)and work of breath(WOB)in observation group were lower than those in control group,and the differences were statistically significant(P＜0.05).The mean airway pressure(MAP),tidal volume(VTi)and minute ventilation volume(M Vi)after treatment were no statistically significant between the two groups(P＞0.05).The inspiratory trigger delay time in the observation group was shorter than that in the control group,the difference was sta-tistically significant(P＜0.05).There was no significant difference in the total incidence of complications between the two groups(P＞0.05).Conclusion NAVA treatment for neonatal NARDS can achieve significant disease treatment effect.Com-pared with SIMV mode,NAVA can improve man-machine coordination,reduce respiratory work,and reduce airway peak pressure level,which is relatively safe and reliable.
维普
万方数据