Effect of 0.1 mg/kg Nalbuphine combined with Etomidate anesthesia on hemodynamic parameters and safety in patients undergoing non convulsive electroconvulsive therapy
Effect of 0.1 mg/kg Nalbuphine combined with Etomidate anesthesia on hemodynamic parameters and safety in patients undergoing non convulsive electroconvulsive therapy
Objective To explore the effect of 0.1 mg/kg Naborphanine combined with Etomidate anesthesia on hemodynamic indicators and safety in patients undergoing non convulsive electroconvulsive therapy(MECT).Methods A total of 96 patients who received MECT treatment in the Third People's Hospital of Ganzhou from March 2022 to October 2023 were selected as the study objects and divided into control group(32 cases),study group 1(32 cases)and study group 2(32 cases)by drawing lots.The control group was anesthetized with 2 ml of physiological saline and Etomidate.Study group 1 was anesthetized with 0.05 mg/kg of Nalbuphine and Etomidate,while study group 2 was anesthetized with 0.1 mg/kg of Nalbuphine and Etomidate.The hemodynamic indexes(mean arterial pressure[MAP],heart rate[HR])before anesthesia(T0),after anesthesia induction(T1),5 min after MECT treatment(T2),and at the end of MECT treatment(T3),quality of recovery,myoclonus degree and adverse reactions of the three groups were compared.Results MAP and HR of T1～T3 in study group 1 and study group 2 were lower than those in control group,and the difference was statistically significant(P＜0.05).There was no significant difference in the recovery time of consciousness and spontaneous respiration among the three groups(P＞0.05).The severity of myoclonus in study group 2 was less than that in study group 1 and control group,and the difference was statistically significant(P＜0.05).The total incidence of adverse reactions in study group 2 was lower than that in control group,and the difference was statistically significant(P＜0.05).Conclusion The use of 0.1 mg/kg Nalbuphine combined with Etomidate anesthesia in patients undergoing MECT treatment can stabilize hemodynamics,reduce the severity of myoclonus,reduce the occurrence of adverse reactions,and have little impact on awakening quality.
关键词
无抽搐电休克/纳布啡/依托咪酯/血流动力学指标
Key words
Non convulsive electroconvulsive therapy/Nabphine/Etomidate/Hemodynamic indicators
维普
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