Comparison of safety between total intravenous general anesthesia and in-travenous compound Sevoflurane inhalation general anesthesia in pedi-atric anesthesia
Comparison of safety between total intravenous general anesthesia and in-travenous compound Sevoflurane inhalation general anesthesia in pedi-atric anesthesia
Objective To explore the effect of total intravenous general anesthesia and intravenous compound Sevoflurane inhalation general anesthesia in pediatric anesthesia.Methods Sixty surgical children admitted to Rizhao Hospital of Tradi-tional Chinese Medicine from September 2022 to September 2023 were selected as the study objects,and were divided into control group and observation group by random number table method,with 30 cases in each group.The children in the con-trol group were given Propofol total intravenous anesthesia,while the children in the observation group were given intra-venous Sevoflurane inhalation general anesthesia.Hemodynamic indexes,postoperative recovery,stress response indexes,delirium and incidence of adverse reactions were compared between the two groups.Results The mean arterial pressure(MAP),heart rate(HR)during operation,and blood oxygen saturation(SpO2)during and 20 min after operation in the obser-vation group were higher than those in the control group and the differences were statistically significant(P＜0.05).The ex-tubation time,orientation recovery time and recovery time of the observation group were shorter than those of the control group,and the intubation time and loss of consciousness were longer than those of the control group,the differences were statistically significant(P＜0.05).The serum levels of norepinephrine(NE),epinephrine(E)and cortisol(Cor)in the obser-vation group were higher than those in the control group 20 min after trachea extubation,and the differences were statisti-cally significant(P＜0.05).Pediatric anesthesia emergence delirium(PAED)scale score 3 days after surgery in the observa-tion group was lower than that in the control group,and the difference was statistically significant(P＜0.05).The total inci-dence of adverse reactions in observation group was lower than that in control group,and the difference was statistically sig-nificant(P＜0.05).Conclusion The implementation of intravenous combined Sevoflurane inhalation general anesthesia in pediatric anesthesia can better stabilize intraoperative hemodynamics,quickly awaken and recover after surgery,reduce the incidence of postoperative delirium,and ensure safety.However,total intravenous anesthesia with Propofol can alleviate the stress response in perioperative period.
关键词
全凭静脉全身麻醉/静脉复合麻醉/七氟烷吸入/小儿麻醉
Key words
Total intravenous general anesthesia/Intravenous compound anesthesia/Inhalation of sevoflurane/Pediatric anesthesia
维普
万方数据