Objective To analyze the epidemiological characteristics and etiological surveillance of hand,foot and mouth disease,and to provide scientific basis for improving the quality of surveillance and formulating prevention and control mea-sures.Methods The cases of hand,foot and mouth disease reported by law from 2019 to 2023 in Yantai Economic and Technological Development Zone were selected as the research objects.The concentration and seasonal index methods were used to analyze the distribution of hand,foot and mouth disease and the influence of sample collection and detection time on the quality of etiological surveillance.Results A total of 934 cases of HFMD were reported from 2019 to 2023,with an aver-age annual incidence of 45.43 per 100 000.The number of cases of HFMD in Fulai Mountain street was higher than that in other towns,and the difference was statistically significant(P＜0.05).The seasonal concentration M value was 0.64,and the seasonal index C value was greater than 100％from June to September.There were 659 cases of HFMD in children aged 1 to 5 years,and 753 cases in scattered children and children in kindergartens.The incidence rate of students and other popula-tion from 2022 to 2023 was higher than that from 2019 to 2021.There were 568 cases of HFMD in males and 366 cases in females.There was no significant difference in incidence between males and females(P＞0.05).Among 377 samples of HFDS,260 were positive for Enteroviruses(EV)(68.97％),among which the positive numbers of EV A71,Coxsackievirus(CV)A16 and other EV accounted for 5.00％(13/260),19.62％(51/260)and 75.38％(196/260),respectively.The lowest positive rate was 59.46％after the onset of disease ≥7 days,and the highest positive rate was 84.48％within 0-10 days af-ter sampling,with statistical significance(P＜0.05).Conclusion The epidemic season of hand,foot and mouth disease is from June to September in Yantai Economic and Technological Development Zone,and the age composition ratio and pathogen spectrum of hand,foot and mouth disease were changed.
关键词
手足口病/流行病学/集中度/季节指数/病原学
Key words
Hand,foot and mouth disease/Epidemiology/Concentration/Seasonal index/Aetiology
维普
万方数据