Characteristics of intravascular ultrasound calcification in patients with acute coronary syndrome and influencing factors of restenosis after per-cutaneous coronary intervention
Objective To investigate the characteristics of intravascular ultrasound(IVUS)calcification and the influencing factors of restenosis after percutaneous coronary intervention(PCI)in patients with acute coronary syndrome(ACS).Meth-ods A total of 203 patients with ACS admitted to Pingxiang NO.2 People's Hospital from April 2021 to February 2023 were selected as the study objects.All patients received PCI treatment,and underwent IVUS examination after PCI to observe the calcification characteristics,followed up for 9 months,and underwent postoperative restenosis coronary angiography.Ac-cording to restenosis,the patients were divided into restenosis group and non-restenosis group,and the relationship between calcification and postoperative stenosis was analyzed.Results Among 203 patients with ACS,postoperative stenosis oc-curred in 19 cases 9 months after PCI,and the incidence of restenosis was 9.36%.There were 16 cases of calcification in the restenosis group and 103 cases in the non-restenosis group.The incidence of calcification in the restenosis group was higher than that in the non-restenosis group,and the difference was statistically significant(P<0.05).In the patients with calcifi-cation,the type of superficial calcification in the restenosis group was higher than that in the non-restenosis group,and the length and arc of calcification were higher than those in the non-restenosis group,with statistical significance(P<0.05).Multivariate logistic regression model analysis showed that calcification lesion(β=0.593,OR=1.809,95%CI:1.206-2.715),calcification type(β=0.414,OR=1.513,95%CI:1.175-1.948),calcification length(β=0.377,OR=1.458,95%CI:1.189-1.788)and arc of calcification(β=0.185,OR=1.203,95%CI:1.055-1.372)were the independent influencing factors for restenosis in ACS patients after PCI(P<0.05).Conclusion The occurrence of calcification in ACS patients can increase the risk of restenosis after PCI,and it is related to the type,length and arc of calcification.