Study on the application of sedative and depression-relieving medicine pillow combined with repetitive transcranial magnetic stimulation in pa-tients with mild cognitive impairment
Study on the application of sedative and depression-relieving medicine pillow combined with repetitive transcranial magnetic stimulation in pa-tients with mild cognitive impairment
Objective To analyze the application effect of sedative and depression-relieving medicine pillow combined with repetitive transcranial magnetic stimulation in patients with mild cognitive impairment.Methods A total of 50 patients with mild cognitive impairment admitted to Shenzhen Hospital of Guangzhou University of Chinese Medicine from January to De-cember 2023 were selected as the research objects.According to the random number table method,they were divided into control group and observation group,with 25 cases in each group.The control group was treated with conventional drugs+repetitive transcranial magnetic stimulation,and the observation group was treated with conventional drugs+repetitive tran-scranial magnetic stimulation+sedative and depression-relieving medicine pillow.The total effective rate,mini-mental state examination(MMSE),Montreal cognitive assessment(MoCA),Pittsburgh sleep quality index(PSQI)and safety were compared between the two groups.Results The total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P＜0.05).Before treatment,there were no statistically significant dif-ferences in MMSE,MoCA and PSQI scores between the two groups(P＞0.05).After treatment,the MMSE and MoCA scores of the observation group were higher than those of the control group,and the PSQI score was lower than that of the control group,and the differences were statistically significant(P＜0.05).During the treatment,there were no related adverse events in the observation group,and 4 cases(16.00％)of adverse events occurred in the control group(1 case of peritonitis,1 case of electrolyte disturbance,and 2 cases of ear fullness).The total incidence of adverse events in the observation group was lower than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion The sedative and depression-relieving medicine pillow combined with repetitive transcranial magnetic stimulation in the treatment of mild cognitive impairment has significant clinical efficacy and good safety,which is worthy of clinical promotion.
关键词
安神解郁药枕/重复经颅磁刺激/轻度认知障碍/应用效果
Key words
Sedative and depression-relieving medicine pillow/Repetitive transcranial magnetic stimulation/Mild cognitive impairment/Application effect
维普
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