At present,metabolic dysfunction associated steatotic liver disease(MASLD)has become the main cause of chronic liver disease worldwide and China.MASLD may develop into liver fibrosis,cirrhosis,and hepatocellular carcinoma.Liver fibrosis is the key determinant of liver related mortality and all-cause mortality in MASLD patients.Only patients at risk of progression need to be managed by gastroenterology or hepatology center,while the other patients only need to undergo weight management and regular follow-up.Most patients with steatotic liver in our country are found during physical examinations,so it is crucial for examination centers and other medical institutions to conduct preliminary evaluations of liver fibrosis in patients.This article mainly introduces how clinical physicians evaluate the risk of disease progression in MASLD patients,in order to provide a reasonable management plan and avoid missed diagnosis and excessive treatment.
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