摘要
目的:探讨贵阳市582例围绝经期女性睡眠与血压的关系,为预防围绝经期女性高血压提供参考依据.方法:随机抽样的贵州医科大学附属医院体检中心582名体检女性测量身高、体重、血压并进行问卷调查,内容包括一般情况、饮食及运动情况,月经情况、改良Kupperman评分表以及匹兹堡睡眠质量指数量表(PSQI).清晨空腹静脉采血检测葡萄糖、血清总胆固醇、甘油三酯、高密度脂蛋白胆固醇及低密度脂蛋白胆固醇.结果:不同年龄、月经情况、测血压频率及总胆固醇水平情况时女性收缩压和舒张压不同,差异均有统计学意义(P值均<0.05).不同入睡难易程度、睡眠时间、是否存在睡眠障碍、睡眠质量女性的收缩压和舒张压差异均有统计学意义(P值均<0.05).不同主观睡眠质量、不同睡眠效率、是否使用催眠药物、是否存在日间功能障碍血压水平差异无统计学意义(P值均>0.05).在调整年龄、体育锻炼、体质量指数(BMI)、月经情况、测血压频率、饮食口味等因素的多元线性回归模型中,睡眠质量与收缩压(β=4.407,P<0.001)、舒张压(β=3.380,P<0.001)的关联均有统计学意义.结论:睡眠质量差的女性收缩压和舒张压高于睡眠质量好的女性,提高围绝经期女性睡眠质量可能有利于预防血压升高.
Abstract
Objective:To explore the relationship between sleep and blood pressure in 582 perimenopausal women in Guiyang,and to provide reference basis for the prevention of hypertension in perimenopausal women.Methods:A random sample of 582 physical examination women in the physical examination center of the Affiliated Hospital of Guizhou Medical University measured their height,weight and blood pressure,and conducted a questionnaire survey,including general conditions,diet and exercise,menstruation,the improved Kupperman score and Pittsburgh sleep quality index(PSQI).Fasting venous blood was collected in the morning to detect glucose,serum total cholesterol triglyceride,high density lipoprotein and low density lipoprotein.Results:There were significant differences in systolic and diastolic blood pressure among women with different age,menstrual conditions,blood pressure frequency and total cholesterol(P<0.05).Stratified analysis of confounding factors and sleep quality showed no significant difference(P>0.05).There were significant differences in systolic and diastolic blood pressure among women with different difficulty in falling asleep,sleep time,whether there was sleep disorder and sleep quality(P<0.05).There was no significant difference in blood pressure between different subjective sleep quality,different sleep efficiency,whether hypnotic drugs were used and whether there was daytime dysfunction(P>0.05).In the multiple linear regression model adjusted for age,physical exercise,BMI,menstruation,blood pressure measurement frequency,dietary taste and other factors,sleep quality and systolic blood pressure(β=4.407,P<0.01),diastolic blood pressure(β=3.380,P<0.01).Conclusion:The systolic blood pressure and diastolic blood pressure of women with poor sleep quality are higher than those with good sleep quality.Improving the sleep quality of perimenopausal women may be helpful to prevent the rise of blood pressure.