健康体检与管理2024，Vol.5Issue(4) ：364-370.

健康体检人群颈动脉内中膜增厚及斑块形成危险因素的分析

Analysis of risk factors for carotid intima-media thickening and plaque formation in the population undergoing health check ups

王萍 徐丽娟 向红雨 雷蒲俊 陈敏哲 邱心怡 肖易
健康体检与管理2024，Vol.5Issue(4) ：364-370.
✕
  • 维普
  • 万方数据

健康体检人群颈动脉内中膜增厚及斑块形成危险因素的分析

Analysis of risk factors for carotid intima-media thickening and plaque formation in the population undergoing health check ups

王萍 1徐丽娟 2向红雨 2雷蒲俊 1陈敏哲 1邱心怡 1肖易1
扫码查看

作者信息

  • 1. 湖北省赤壁市疾病预防控制中心,湖北 赤壁 437300
  • 2. 湖北省武汉大学人民医院健康管理中心,湖北 武汉 430000
  • 折叠

摘要

目的:通过分析健康体检人群中颈动脉内中膜(CIMT)增厚及颈动脉斑块的检出率与血糖、血脂、血压之间的关系,探讨CIMT增厚及颈动脉斑块相关危险因素,为动脉粥样硬化的一级预防提供理论基础.方法:筛选并纳入2018-2021年内赤壁市35岁及以上在健康管理中心参与体检的人群4 179例.回顾性收集颈动脉超声、血脂四项[包括总胆固醇(TC)、甘油三酯(TG),高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)]、血糖、血压等体检指标结果,并分析CIMT增厚及颈动脉斑块与上述指标的相关性.结果:多因素Logistic回归分析结果显示,CIMT增厚的独立危险因素包括:年龄增长(如45～54岁组OR=2.030,95%CI 1.416～2.911;55～64岁组OR=4.401,95%CI 3.102～6.246等)、男性性别(OR=0.506,95%CI 0.459～0.557,作为保护因素,实际危险因素为男性)、血糖升高(OR=1.210,95%CI 1.098～1.334)、收缩压升高(OR=1.400,95%CI 1.256～1.559)及TC升高(OR=1.431,95%CI 1.298～1.577),所有P值均＜0.01.颈动脉斑块形成的独立危险因素包括:年龄增长(如45～54岁组OR=3.365,95%CI 2.063～5.491;55～64岁组OR=8.348,95%CI 5.167～13.489等)、男性性别(OR=0.615,95%CI 0.560～0.676,作为保护因素,实际危险因素为男性)、血糖升高(OR=1.620,95%CI 1.475～1.780)及收缩压升高(OR=2.157,95%CI 1.944～2.394),所有P值均＜0.01.结论:健康体检人群中CIMT增厚及斑块的发生率与高血糖、高血脂、高血压密切相关,发生率随年龄的增加升高,且男性高于女性.

Abstract

Objective:To understand the detection rate of carotid intima-media thickness(CIMT)and carotid plaque in healthy people,analyze the relationship with blood sugar,blood lipid and blood pressure,and explore its related risk factors,so as to provide a theoretical basis for primary prevention of atherosclerosis.Methods:4 179 people over 35 years old who participated in physical examination in health management centers in Chibi City from 2018 to 2021 were screened and included.The results of carotid ultrasound,blood lipid(total cholesterol(TC),triglyceride(TG),including high density lipoprotein cholesterol(HDL-C)and low density lipoprotein cholesterol(LDL-C),blood sugar test and blood pressure were collected retrospectively.Results:Among 4 179 physical examination people,there were statistically significant correlations between CIMT thickening group,plaque group and normal group with blood sugar,blood pressure,TC,TG and HDL-C.At the same time,with the increase of age,the prevalence of CIMT and plaque increased,and the prevalence rate of men was higher than that of women.Conclusion:The incidence of CIMT and plaque in healthy people is closely related to hyperglycemia,hyperlipidemia and hypertension,and the incidence increases with age,and males are higher than females.

关键词

健康体检人群/颈动脉斑块/血糖/血脂/危险因素

Key words

Health check-up population/Carotid artery plaque/Blood sugar/Blood lipids/Risk factors

引用本文复制引用

出版年

2024
健康体检与管理
中国医院协会

健康体检与管理

ISSN：2096-9449
段落导航相关论文