中国健康心理学杂志2024，Vol.32Issue(8) ：1186-1190.DOI:10.13342/j.cnki.cjhp.2024.08.012

肝癌首次化疗患者生活质量与负性情绪的关系及影响因素

Influencing factors of quality of life in patients with liver cancer undergoing first chemotherapy and their relationship

董玲玲 古小改 郝娜 张丽 岳颖
中国健康心理学杂志2024，Vol.32Issue(8) ：1186-1190.DOI:10.13342/j.cnki.cjhp.2024.08.012
✕
  • 维普
  • 万方数据

肝癌首次化疗患者生活质量与负性情绪的关系及影响因素

Influencing factors of quality of life in patients with liver cancer undergoing first chemotherapy and their relationship

董玲玲 1古小改 1郝娜 2张丽 3岳颖4
扫码查看

作者信息

  • 1. 郑州大学第二附属医院消化内科三病区 450003
  • 2. 郑州大学第二附属医院消化内科二病区
  • 3. 郑州大学第二附属医院护理部
  • 4. 郑州市第七人民医院检验科
  • 折叠

摘要

目的:分析肝癌首次化疗患者生活质量的影响因素.方法:选择2021年6月-2023年6月收治的60例肝癌患者,收集患者年龄、性别等一般资料,并采用肝癌患者生活质量量表(QOL—LC)、汉密顿焦虑量表(HA-MA)、汉密顿抑郁量表(HAMD)、社会支持评定量表(SSRS)、家庭关怀度量表(APGAR)评估患者生活质量、负性情绪、社会支持水平及家庭关怀度,采用单因素分析及多因素Logistic回归分析肝癌患者生活质量的影响因素,采用pearson相关性分析肝癌患者生活质量与负性情绪、社会支持水平及家庭关怀度的关系.结果:60例患者QOL—LC得分范围为107～196分,平均158.93±15.89分.单因素分析显示,独居、卡氏功能评分、HAMA评分、HAMD评分、社会支持度及家庭关怀度均是肝癌患者生活质量的影响因素(t=2.032,2.876,61.499,63.672,79.097,82.342;P＜0.05).多因素Logistic回归分析显示,焦虑、抑郁、低水平社会支持是肝癌患者生活质量的独立危险因素(OR=3.888,3.418,0.291;95％置信区间为 1.423～10.628,1.509～7.739,0.141～0.599).pearson 相关性分析显示,肝癌患者QOL—LC评分与HAMA评分、HAMD评分均呈负相关关系(r=-0.428,-0.475;P＜0.001),与SSRS评分、APGAR评分呈正相关关系(r=0.524,0.537;P＜0.001).结论:心理状况、社会支持度均是肝癌首次化疗患者生活质量的独立影响因素.

Abstract

Objective:To analyze the influencing factors of quality of life in patients with liver cancer undergoing first chemotherapy.Methods:A total of 60 patients with liver cancer admitted from June 2021 to June 2023 were se-lected.The general data such as age and gender of patients were collected.The quality of life,negative emotions,social support level and family care degree of patients were evaluated by Quality of Life Scale for Liver Cancer(QOL—LC),Hamilton Anxiety Scale(HAMA),Hamilton Depression Scale(HAMD),Social Support Rating Scale(SSRS)and Family APGAR Index(APGAR).Univariate analysis and multivariate Logistic regression analysis were used to analyze the influencing factors of quality of life in patients with liver cancer.Pearson correlation analysis was applied to analyze the relationship of quality of life with negative emotions,social support level and family care degree in pa-tients with liver cancer.Results:The QOL—LC score of 60 patients ranged from 107 to 196 points,with an average of(158.93±15.89)points.Univariate analysis showed that living alone,Karnofsky performance score,HAMA score,HAMD score,social support and family care degree were the influencing factors of quality of life in patients with liv-er cancer(t=2.032,2.876,61.499,63.672,79.097,82.342;P＜0.05).Multivariate Logistic regression analysis re-vealed that anxiety,depression,low social support level were independent risk factors for quality of life in patients with liver cancer(Or=3.888,3.418,0.291;95％CI=1.423-10.628,1.509-7.739,0.141-0.599).Pearson correlation a-nalysis manifested that QOL—LC score was negatively correlated with HAMA score and HAMD score(r=-0.428,-0.475;P＜0.001),and was positively correlated with SSRS score and APGAR score(r=0.524,0.537;P＜0.001).Conclusion:Psychological status,social support level are independent influencing factors of quality of life in patients with liver cancer undergoing first chemotherapy.

关键词

肝癌/化疗/生活质量/负性情绪/社会支持/家庭关怀度

Key words

Liver cancer/Chemotherapy/Quality of life/Negative emotions/Social support/Family care degree

引用本文复制引用

基金项目

2020年河南省医学科技攻关计划联合共建项目(LHG T20200731)

出版年

2024
中国健康心理学杂志
中国心理卫生协会

中国健康心理学杂志

影响因子：1.264
ISSN：1005-1252
段落导航相关论文