目的:对比分析双相抑郁(BD)与单相抑郁(UD)患者心理学特征与认知功能差异。方法:选取某院2023年1月至2024年4月就诊的BD患者60例(BD组)、UD患者60例(UD组)。采集对比各组人口学相关信息，选择汉密尔顿抑郁量表(HAMD)-17、汉密尔顿焦虑量表(HAMA)及艾森克人格问卷(EPQ)对患者心理评估，且经由蒙特利尔认知评估量表(MoCA)、Stroop色词测验评估各组患者认知功能;Pearson相关性分析心理特征相关量表评分与MoCA总分的关系。结果:BD组病程长于UD组(t=3。573，P＜0。01)，有自杀风险比例小于UD组(x2=11。109，P＜0。01)，性别、年龄等其他人口学指标对比无统计学差异(P＞0。05)。两组HAMD-17、HAMA评分对比无统计学差异(P＞0。05)。BD组EPQ中N评分、E评分均高于UD组(t=2。927，5。153;P＜0。05)。BD组MoCA量表中延迟回忆、视空间执行能力评分及总分均低于UD组(t=6。263，4。365，6。787;P＜0。01)。BD组Stroop色词测验中颜色评分低于UD组(t=2。274，P＜0。05)，词汇、色词干扰评分对比无统计学差异(P＞0。05)。BD组与UD组患者MoCA总分与HAMD-17评分、HAMA评分、EPQ中P、N、E评分均负相关(r=-0。600，-0。642，-0。520，-0。503，-0。528，-0。482，-0。543，-0。495，-0。506，-0。487;P＜0。05)。结论:BD 相比 UD 病程较长，EPQ 上倾向外向、情绪不稳的人格;BD患者延迟回忆、视空间执行能力及整体认知功能损伤重于UD患者，但后者自杀风险大。
Analysis of psychological characteristics and cognitive function differences between bipolar depression and unipolar depression
Objective:To compare and analyze the psychological characteristics and cognitive function differences of patients with bipolar depression(BD)and unipolar depression(UD).Methods:A total of 60 BD patients(BD group)and 60 UD patients(UD group)were selected from January 2023 to April 2024.Demographic information of each group was collected and compared.Hamilton Depression Scale(HAMD)-17,Hamilton Anxiety Scale(HAMA)and Eysen-ck Personality Questionnaire(EPQ)were selected for psychological assessment.The cognitive function of each group was evaluated by the Montreal Cognitive Assessment Scale(MoCA)and Stroop color-word test.Results:The course of disease in the BD group was longer than that in the UD group(t=3.573,P＜0.01),and the proportion of suicide risk was lower than that in the UD group(x2=11.109,P＜0.01).There was no statistically significant difference in gender,age,and other demographic indicators(P＞0.05).There was no statistically significant difference in HAMD-17 and HAMA scores between the two groups(P＞0.05).The N score and E score in EPQ in the BD group were higher than those in the UD group(t=2.927 and 5.153,both P＜0.05).The scores of delayed recalls,visuospatial ex-ecutive ability,and total score of MoCA in the BD group were lower than those in the UD group(t=6.263,4.365,6.787;P＜0.01).The score of the color in Stroop color-word test group was lower than that in the UD group(t=2.274,P＜0.05),and there was no statistically significant difference in lexical and color word interference scores(P＞0.05).The total MoCA score of patients in the BD group and the UD group was negatively correlated with HAMD-17 score(r=-0.600,-0.642),HAMA score(r=-0.520,-0.503),P(r=-0.528,-0.482),N(r=-0.543,-0.495),E(r=-0.506,-0.487)scores in EPQ(all P＜0.05).Conclusion:Compared with UD,BD has longer course of disease.EPQ tends to be an extroverted,emotionally unstable personality;The impairment in delayed recall,visuospatial executive ability,and overall cognitive function in BD patients is greater than that in UD patients,but the latter has a higher risk of suicide.
Bipolar depressionUnipolar depressionPsychological characteristicsCognitive function
万方数据
维普
