Objective To investigate and analyze the lung function,hemoglobin and oxygen saturation of people in moderate altitude area and low altitude area,and explore the effects of moderate altitude area on human lung function.Methods The data of lung function,hemoglobin and oxygen saturation were collected from moderate altitude areas and low altitude areas,and Pearson correlation analysis was performed to calculate the correlation between age,height and weight and lung function parameters in the two areas.Results There were no statistically significant differences in lung capacity,expiratory capacity,expiratory capacity in one second,one-second rate,and maximal mid-expiratory flow rate between the moderate altitude population and the low altitude population(P>0.05).However,the maximal respiratory flow rate of the moderate altitude population was significantly higher than that of the low altitude population(P<0.05).The Pearson correlation analysis revealed a significant negative correlation between age and lung function in both populations.Additionally,height was positively correlated with expiratory lung capacity,expiratory volume in one second,and maximum mid-expiratory flow rate,while body mass was positively correlated with expiratory lung capacity.All of these correlations were statistically significant(P<0.05).The study found that the oxygen saturation of individuals living in moderate altitude areas was lower than that of those living in low altitude areas,while the haemoglobin levels of individuals living in moderate altitude areas were higher than those of individuals living in low altitude areas.These differences were statistically significant(P<0.05).Conclusions In males from moderate altitude populations,there is a reduction in oxygen saturation and compensatory increases in haemoglobin.Moderate altitude,on the other hand,have reduced respiratory resistance and increased PEF.