基于输血角度的主动脉夹层A型患者预后影响因素分析
Analysis of prognostic factors for patients with type A aortic dissection based on transfusion perspective
粟昭隐 1张红良 2林奕丰 1康巍瀚 1潘毅 3夏黑旦·木塔力甫 3吴国君 1刘瑶 1芦帅 1郑昕1
作者信息
- 1. 兰州大学 第一临床医学院,甘肃 兰州 730000
- 2. 兰州大学第一医院 输血科,甘肃 兰州 730000
- 3. 兰州大学 第二临床医学院,甘肃 兰州 730000
- 折叠
摘要
目的 基于输血角度分析主动脉夹层A型手术患者的预后情况及相关影响因素,为临床提供参考.方法 回顾 199 例主动脉夹层A型手术患者的临床资料,应用单因素分析及多因素Logistic回归分析患者预后不良的相关因素.结果 199 例主动脉夹层A型患者中 159 例预后良好,40 例预后不良,预后不良患者占比 20.1%.单因素分析显示,主动脉夹层A型患者预后不良与围术期输注红细胞量、围术期输注血小板量、住院时长有关(均P<0.05);多元Logistic回归分析显示,围术期红细胞输注量是患者预后不良的独立危险因素,住院天数是患者预后不良的独立保护因素,均P<0.001.结论 围术期输注过多红细胞会提高主动脉夹层A型患者预后不良的风险,适当延长住院时长有助于避免预后不良的情况发生.
Abstract
Objective To analyze the prognosis and related factors influencing patients with Type A aortic dissection from the perspective of blood transfusion,providing clinical references.Methods The clinical data of 199 patients who underwent type A surgery for aortic coarctation were retrospectively analysed.Univariate analysis and multifactorial logistic regression were used to analyse the factors associated with the patients'poor prognosis.Results Out of the 199 patients diagnosed with aortic coarctation type A,159 had a good prognosis,while 40 had a poor prognosis,resulting in a proportion of 20.1%of patients with a poor prognosis.According to the univariate analysis,the poor prognosis of patients with aortic coarctation type A was associated with the quantity of perioperative red blood cell transfusion,the amount of perioperative platelet transfusion,and the length of hospital stay(all P<0.05).A multivariate logistic regression analysis revealed that the amount of perioperative red blood cell transfusion was an independent risk factor for poor patient prognosis(P<0.001).Additionally,the number of days spent in the hospital was found to be an independent protective factor for poor patient prognosis(P<0.001).Conclusions Transfusing excessive red blood cells during perioperative care increases the risk of poor prognosis in patients with aortic coarctation type A.Prolonging the length of hospital stay can be an effective measure to avoid poor prognosis.
关键词
输血/主动脉夹层A型/预后/影响因素Key words
transfusion/type A aortic dissection/prognosis/influencing factors引用本文复制引用
基金项目
兰州大学 2022年大学生创新创业行动计划(20220060178)
出版年
2024
国家科技期刊平台
NSTL
万方数据