早产儿发生低血糖的危险因素分析
Analysis of the risk factors for developing hypoglycemia in preterm infants
吕雯 1俞叶华1
作者信息
- 1. 浙江省诸暨市人民医院 新生儿科,浙江 诸暨 311800
- 折叠
摘要
目的 探究早产儿出生后发生低血糖的危险因素,为早产儿低血糖的预防和管理提供资料.方法 回顾 536例胎龄<37周的早产儿临床资料,统计发生低血糖(血糖低于2.2 mol/L)的病例数,比较低血糖组和正常组的临床资料差异,运用Logistic回归模型分析早产儿发生低血糖的危险因素.结果 536例早产儿发生低血糖 82 例,发生率为15.3%.低血糖组早产儿的胎龄、出生体重低于正常组,小于胎龄儿(SGA)、剖宫产、出生体温<36.5℃、妊娠期甲状腺功能减退、妊娠期糖尿病、妊娠期高血压的比例高于正常组,差异均有统计学意义(P<0.05).Logistic回归分析显示,SGA(OR=1.401)、妊娠期糖尿病(OR=2.746)、妊娠期高血压(OR=1.525)、出生低体温(OR=2.110)为早产儿低血糖的危险因素,阴道分娩(OR=0.596)为早产儿低血糖的保护因素,均P<0.05.结论 SGA、出生低体温、妊娠期高血压、妊娠期糖尿病可增加早产儿低血糖的发生风险,阴道分娩能够降低早产儿低血糖的发生风险.
Abstract
Objective To explore the risk factors of hypoglycemia in premature infants and provide reference for the monitoring and management of neonatal blood glucose.Methods The clinical data of 536 preterm infants with a gestational age of less than 37 weeks were reviewed.The number of cases in which hypoglycaemia(blood glucose less than 2.2 mol/L)occurred was recorded,and the differences in clinical data between the hypoglycaemic and normal groups were compared.Risk factors for hypoglycaemia in preterm infants were analysed using a logistic regression model.Results Hypoglycaemia was observed in 82 out of 536 preterm infants,resulting in an incidence rate of 15.3%.The gestational age and birth weight of preterm infants in the hypoglycaemia group were lower than those in the normal group.Additionally,the proportion of small-for-gestational-age(SGA)infants,caesarean section,birth temperature below 36.5℃,hypothyroidism during pregnancy,gestational diabetes mellitus,and gestational hypertension were higher in the hypoglycaemia group than in the normal group.These differences were statistically significant(P<0.05).The logistic regression analysis showed that preterm infants are at risk of hypoglycaemia due to being small for gestational age(OR= 1.401),gestational diabetes mellitus(OR=2.746),gestational hypertension(OR = 1.525),and birth hypothermia(OR = 2.110),while vaginal delivery(OR= 0.596)is a protective factor against it.All factors were found to be statistically significant(P<0.05).Conclusions Preterm infants are at an increased risk of hypoglycaemia due to SGA,birth hypothermia,gestational hypertension,and gestational diabetes mellitus.Additionally,vaginal delivery has been shown to reduce the risk of hypoglycaemia in preterm infants.
关键词
早产儿/低血糖/危险因素Key words
preterm infants/hypoglycemia/risk factors引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据