Objective Observing the umbilical artery(UA)and middle cerebral artery(MCA)hemodynamic parameters in patients with preterm preeclampsia,and exploring their relationship with pregnancy outcomes.Methods According to the severity of the condition,pregnant women with preeclampsia delivering before 37 weeks of gestation were divided into mild and severe groups.The occurrence of maternal complications and adverse pregnancy outcomes in both groups was recorded.Healthy pregnant women who delivered at the same period in our hospital were selected as the control group.The resistance index(RI),pulsatility index(PI),the ratio of peak systolic velocity to end-diastolic velocity(S/D),and the cerebral-placental ratio(CPR)of the umbilical artery and middle cerebral artery were compared among the three groups.The occurrence rate of adverse pregnancy outcomes and neonatal-related indicators were compared among the groups.According to the pregnancy outcomes,patients were divided into adverse outcome group and non-adverse outcome group,and the clinical data of the two groups were compared.Logistic regression analysis was performed to evaluate the correlation between ultrasound hemodynamics and neonatal prognosis.Results The levels of PI,RI,and S/D in the umbilical artery(UA)were highest in the severe group,followed by the mild group,and lowest in the control group.The levels of PI,RI,and S/D in the middle cerebral artery(MCA)were highest in the control group,followed by the mild group,and lowest in the severe group.The differences among the groups were statistically significant(P<0.001).The occurrence rates of adverse pregnancy outcomes in the control group,mild group,and severe group were 7.5%(3/40),25.0%(10/40),and 37.5%(15/40),respectively.The differences among the three groups were statistically significant(χ2 = 10.155,P<0.001).Regression analysis showed that UA(PI,RI,S/D),MCA(PI,RI,S/D),and CPR were all correlated with poor prognosis in perinatal infants(P<0.05).Conclusions The hemodynamic parameters of the umbilical artery and middle cerebral artery in fetuses have certain clinical value in predicting adverse pregnancy outcomes in patients with preterm preeclampsia.
国家科技期刊平台
NSTL
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