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NICU新生儿营养状态的影响因素分析

Nutritional status and related factors of neonates with maternal separation in NICU

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目的 评估新生儿重症监护室(NICU)新生儿的营养状态,分析其相关因素,以期为临床干预提供依据.方法 收集 920 例NICU住院新生儿的临床资料,按照新生儿入住NICU 7 d时的体重、身长进行营养状态评估,分为营养不良组和营养正常组,采用单因素和多因素回归分析新生儿营养不良的影响因素.结果 920 例新生儿中,年龄别体重Z评分(WAZ)<-2 者157 例(17.07%),年龄别身高Z评分(LAZ)<-2 者212 例(23.04%),Kaup指数<15者 112 例(12.17%),营养不良的新生儿共 97 例(10.54%).单因素分析显示,早产、呼吸窘迫综合征(NRDS)、出生后并发感染、低出生体重、母体妊娠并发症或合并症、机械通气时间、NICU外检查、应用枸橼酸咖啡因、肠内营养(EN)开始时间>12h为NICU住院新生儿营养不良的相关因素(均P<0.05);多因素Logistic回归分析显示,NRDS、早产、出生后并发感染、低出生体重、母体妊娠并发症或合并症、NICU外检查、应用枸橼酸咖啡因、EN开始时间>12 h为NICU新生儿营养不良的独立危险因素(均P<0.05).结论 NICU新生儿的营养状态总体不佳,NRDS、早产、出生后并发感染、低出生体重、母体妊娠并发症或合并症、NICU外检查、应用枸橼酸咖啡因、EN开始时间>12h均可能增加NICU新生儿营养不良的发生风险.
Objective To assess the nutritional status of neonates in the neonatal intensive care unit(NICU)and analyze the associated factors,with the aim of providing a basis for clinical intervention.Methods Collected clinical data from 920 neonates hospitalized in the NICU,and assessed their nutritional status based on weight and length at 7 days after admission to the NICU.The neonates were categorized into two groups:the malnourished group(97 cases)and the well-nourished group(823 cases).Univariate and multivariate regression analyses were conducted to identify the factors influencing neonatal malnutrition.Results Among the 920 neonates,157 cases(17.07%)had a weight-for-age Z-score(WAZ)less than-2,212cases(23.04%)hadalength-for-age Z-score(LAZ)lessthan-2,and112cases(12.17%)hada Kaup index less than 15.A total of 97 neonates(10.54%)were identified as malnourished.Univariate analysis showed that prematurity,respiratory distress syndrome(NRDS),postnatal infection,low birth weight,maternal pregnancy complications or comorbidities,duration of mechanical ventilation,extra-NICU examinations,administration of caffeine citrate,and initiation of enteral nutrition(EN)later than 12 hours were associated factors for malnutrition in hospitalized neonates in the NICU(P<0.05).Multivariate Logistic regression analysis showed that NRDS,prematurity,postnatal infection,low birth weight,maternal pregnancy complications or comorbidities,extra-NICU examinations,administration of caffeine citrate and initiation of EN later than 12 hours were independent risk factors for malnutrition in mother-infant separated neonates in the NICU(P<0.05).Conclusions The overall nutritional status of neonates in the NICU is suboptimal.Conditions such as NRDS,prematurity,postnatal infections,low birth weight,maternal pregnancy complications or comorbidities,extra-NICU examinations,the use of caffeine citrate and EN start time>12h may all increase the risk of malnutrition in neonates hospitalized in the NICU.

neonatal intensive care unitmaternal separationnutritional statusinfluencing factors

郑嫚、王吉、戴方娣

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舟山市妇女儿童医院 NICU,浙江 舟山 316000

新生儿重症监护室 母婴分离 营养状态 影响因素

2024

健康研究
杭州师范大学

健康研究

影响因子:0.823
ISSN:1674-6449
年,卷(期):2024.44(3)