摘要
目的 分析老年心脑血管疾病患者并发认知障碍的影响因素及干预对策.方法 根据中文版简易智能状态检查量表,评估200例老年心脑血管疾病患者合并认知障碍的情况.比较是否合并认知障碍患者间的一般资料、生化指标结果,分析老年心脑血管疾病患者发生认知障碍的影响因素.结果 200例老年心脑血管疾病患者的认知障碍发生率为35.5%,是否合并认知障碍患者间的年龄、文化程度、有氧运动、高血压、脑卒中情况和同型半胱氨酸(Hcy)水平差异有统计学意义(P<0.05).多因素Logistic回归分析显示,年龄、文化程度、有氧运动、高血压、脑卒中及Hcy水平是认知功能障碍的影响因素(均P<0.05).结论 年龄、文化程度、有氧运动、高血压、脑卒中及Hcy水平与老年心脑血管疾病患者发生认知功能障碍呈相关性,需采取有效防治措施以改善认知功能.
Abstract
Objective To analyze the influencing factors and intervention strategies for cognitive dysfunction in elderly patients with cardiovascular and cerebrovascular diseases.Methods Based on the Chinese version of the mini-mental state examination(MMSE),200 elderly patients with cardiovascular and cerebrovascular diseases were assessed for the presence of cognitive impairment.General information and biochemical indicator results were compared between patients with and without cognitive impairment to analyze the influencing factors of cognitive impairment in elderly patients with cardiovascular and cerebrovascular diseases.Results The incidence of cognitive impairment among the 200 elderly patients with cardiovascular and cerebrovascular diseases was 35.5%.There were statistically significant differences in age,education level,aerobic exercise,hypertension,history of stroke,and homocysteine(Hcy)levels between patients with and without cognitive impairment(P<0.05).Multivariate Logistic regression analysis revealed that age,education level,aerobic exercise,hypertension,history of stroke,and Hcy levels were influencing factors of cognitive dysfunction(all P<0.05).Conclusions Age,education level,aerobic exercise,hypertension,history of stroke,and Hcy levels are significantly correlated with the occurrence of cognitive dysfunction in elderly patients with cardiovascular and cerebrovascular diseases.Effective prevention and treatment measures should be taken to improve cognitive function.