健康研究2024,Vol.44Issue(5) :595-600.DOI:10.19890/j.cnki.issn1674-6449.2024.05.024

冠心病患者经皮冠状动脉介入术后恐动症的影响因素和预测

Factors influencing and predicting agoraphobia after percutaneous coronary intervention in patients with coronary artery disease

赵玲 吴玲霞 马丽 吴甜 陈超
健康研究2024,Vol.44Issue(5) :595-600.DOI:10.19890/j.cnki.issn1674-6449.2024.05.024

冠心病患者经皮冠状动脉介入术后恐动症的影响因素和预测

Factors influencing and predicting agoraphobia after percutaneous coronary intervention in patients with coronary artery disease

赵玲 1吴玲霞 1马丽 1吴甜 1陈超1
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作者信息

  • 1. 杭州市中医院心血管内科,浙江 杭州 310007
  • 折叠

摘要

目的 探讨冠心病经皮冠状动脉介入(percutaneous coronary intervention,PCI)术后患者发生恐动症的危险因素,并构建相关预测模型,为临床早期识别和干预PCI术后恐动症提供依据.方法 收集141例冠心病PCI术后患者的临床资料,根据是否发生恐动症将其分为恐动症组(47例)和非恐动症组(94例),比较2组患者资料;采用多因素Logistic回归,分析冠心病PCI术后患者发生恐动症的危险因素,并构建相关预测模型,用受试者工作特征曲线(ROC)分析预测模型对冠心病PCI术后患者发生恐动症的预测价值.结果 恐动症组与非恐动症组的心力衰竭、家庭功能、自我感受负担情况,及疼痛程度、疲劳程度、社会支持程度比较,差异有统计学意义(P<0.05).Lo-gistic 回归分析结果显示,心力衰竭(OR=4.104)、家庭功能严重障碍(OR=8.542)、重度自我感受负担(OR=4.043)、重度/极重度疼痛(OR=6.600)、重度/极重度疲劳(OR=4.702)、社会支持程度低(OR=3.963),是冠心病PCI术后患者发生恐动症的独立危险因素(均P<0.05).ROC曲线分析结果显示,构建的预测模型对冠心病患者PCI术后发生恐动症的预测价值较好:当logit(P)>11.23时,曲线下面积(AUC)值为0.926,敏感度为87.23%,特异度为89.36%.结论 冠心病PCI术后患者发生恐动症与心力衰竭、家庭功能、自我感受负担、疼痛程度、疲劳程度、社会支持程度有关,临床可据此给予针对性的干预措施,以预防冠心病患者PCI术后发生恐动症.

Abstract

Objective To investigate the risk factors for the occurrence of agoraphobia in patients after Percutaneous coronary intervention(PCI)for coronary artery disease,and to construct a relevant prediction model to provide a basis for early clinical identification and intervention of agoraphobia after PCI.Methods This paper was a cross-sectional survey,the clinical data of 141 post-coronary PCI patients were collected,and they were divided into the agoraphobia group(47 cases)and the non-agoraphobia group(94 cases)according to whether or not agoraphobia occurred,and the data of the 2 groups of patients were compared.Multivariate Logistic regression analysis was utilized to identify the risk factors associated with the development of agoraphobia post-PCI.A predictive model was developed,and the predictive value of this model for agoraphobia in post-PCI patients was assessed using the receiver operating characteristic(ROC)curve analysis.Results Comparison of heart failure,family functioning,and self-perceived burden,as well as pain level,fatigue level,and social support level between the agoraphobia group and the non-agoraphobia group showed statistically significant differences(P<0.05).Logistic regression analysis showed that heart failure(OR=4.104),severe family dysfunction(OR=8.542),severe self-perceived burden(OR=4.043),severe/very severe pain(OR=6.600),severe/very severe fatigue(OR=4.702),and low social support(OR=3.963),were independent risk factors for the occurrence of agoraphobia in patients with coronary artery disease after PCI(all P<0.05).The ROC curve analysis indicated that the predictive model had a good predictive value for agoraphobia in post-PCI patients:when logit(P)>11.23,the Area Under the Curve(AUC)value was 0.926,the sensitivity was 87.23%,and the specificity was 89.36%.Conclusions The occurrence of agoraphobia in patients after PCI for coronary artery disease were related to heart failure,family dysfunction,self-perceived burden,pain level,fatigue level,and social support level.Clinically,targeted intervention measures can be developed based on these factors to prevent the onset of agoraphobia in patients with coronary artery disease after PC1.

关键词

冠心病/经皮冠状动脉介入/恐动症/危险因素/预测

Key words

coronary heart disease/percutaneous coronary intervention/agoraphobia/risk factors/prediction

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出版年

2024
健康研究
杭州师范大学

健康研究

影响因子:0.823
ISSN:1674-6449
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