Research Advances in Biosynthesis of Sophorolipids and Genetic Breeding of High-yield Strains
As a type of glycolipid biosurfactant,sophorolipids have good surface activity and stabil-ity.In particular,sophorolipids with certain structures exhibit biological activities such as antibacte-rial,anti-inflammatory,and antitumor activities while possessing excellent characteristics such as low toxicity,good biocompatibility,and biodegradability,demonstrating important research value and application potential in multiple fields.Herein,the production strains and their product characteris-tics of sophorolipids were discussed,and the research progress of high-yield strain Starmerella bom-bicola in improving its substrate conversion rate and product diversity through genetic modification was reviewed,including traditional breeding and genetic engineering breeding.On this basis,pros-pects were made for further transformation of Starmerella bombicola.
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维普
