The impact of sepsis on long-term cardiovascular events in surviving adult patients
Objective:To clarify the impact of a first-time hospitalization history of sepsis(her einafter referred to as sepsis)on long-term cardiovascular events in surviving adult patients.Methods:Applying queue research methods.According to the 1∶2 case-control matching principle,sepsis patients hospitalized in our hospital and non sepsis patients hospitalized in the same period were selected as the research subjects.Follow-up studies were conducted on two groups of patients after discharge.Recorded the incidence and mortality of cardiovascular diseases in two groups of patients during the follow-up period.Applying Logistic regression analysis to explore the impact of hospitalization history leading to sepsis on cardiovascular events.Results:Multivariate Logistic regression showed that:①Outcome of myocardial infarction:family history of heart disease,history of diabetes mellitus and hospitalization history of sepsis were significant influence factors of myocardial infarction during the follow-up period(P<0.05).OR were 2.012,2.436,1.473.②Outcome of stroke:hypertension,hyperlipidemia,history of stroke and hospitalization history of sepsis were significant influence factors of stroke during follow-up period.OR were 1.392,3.141,1.893,1.428.③Cardiovascular death outcome:older age,diabetes mellitus,low BMI and sepsis hospitalization history were significant influence factors of cardiovascular death during the follow-up period.OR were 2.013,1.876,1.592,1.404.④All-cause death outcome:older age,male,hypertension,diabetes mellitus,active malignant tumor,smoking,and sepsis hospitalization history were significant influence factors of all-cause death during the follow-up period.OR were 2.446,1.229,2.398,1.892,2.713,1.455,1.454.Conclusion:Compared to non sepsis hospitalized survivors,adult sepsis survivors have an increased risk of experiencing cardiovascular events.
sepsishistory of hospitalizationcardiovascular events
万方数据
维普
