The application of body surface area-based individualized iodine contrast agent injection protocol in coronary computed tomography angiography enhancing performance
Objective:To explore the body surface area(BSA)-based individualized iodine contrast agent protocol in coronary computed tomography angiography(CTA).Methods:Thirty patients suspected of having coronary artery disease were randomly allocated into two groups based on body surface area(BSA):Large BSA group comprised individuals with BSA below 1.6 m2,while small BSA group B included those with BSA equal to or above 1.6 m2.The dosage of iodine contrast agents was calculated based on BSA×10/iodine concentration,the injection time of the contrast agent is 10 s.Coronary arteries were imaged in the patient's free breathing state using Revolution CT.Radiologists with over 5 years chest imaging diagnosis experience scored the subjective and objective image quality.CT images were subjectively evaluated by the five-point scale,and objectively measured by the CT values and SNR values of the six main blood vessels,including descending aorta,ascending aorta,left coronary artery,left anterior descending artery,left circumflex branch and right coronary artery.Results:The subjective assessment revealed that both groups of images obtained scores exceeding 3 points,meeting diagnostic criteria.Moreover,there was good agreement between the intraclass correlation coefficient(ICC)values of the two physicians(0.81 and 0.71,respectively).Objective evaluation demonstrated satisfactory visualization of coronary arteries in both image sets.Additionally,there were no statistically significant differences in coronary artery CT values and SNR measurements between the two groups(P>0.05).Conclusion:BSA-based individualized contrast agent injection protocol showed clinical feasibility,and the degree of enhancement of the coronary arteries is appropriate and uniform,meeting clinical diagnostic requirements.
body surface areacoronary arterycomputed tomography angiography(CTA)iodine contrast mediaRevolution CT
万方数据
维普
