Comparison of abbreviated protocols and standard protocol of magnetic resonance imaging in breast cancer screening
Objective:To evaluate the clinical utility of abbreviated protocols(AP)of magnetic resonance protocols(MRI)in the detection of breast cancer.Methods:A total of 193 lesions were retrospectively collected from 186 cases of breast routine MRI with pathological results.Radiologists reviewed the images with three protocols respectively,including the standard full diagnostic protocol(FDP),Ap1[consisting of diffusion-weighted imaging(DWI),pre-and the first postcontrast acquisition with derived images(postcontrast subtracted images)],and AP2[consisting of DWI,pre-,the first and the second postcontrast acquisition with derived images(subtracted images)].The scanning time,imaging reading time and diagnostic performance indexes of above three protocols were compared respectively.Results:The scanning time and imaging reading time of AP1 and AP2 were shorter than FDP(P<0.001).The sensitivity of the three protocols were AP1(80.9%),FDP(93.3%)and AP2(96.6%)respectively.There was no significant difference in AP1 vs.AP2(P=0.104)and AP2 vs.FDP(P=0.305),but the sensitivity of AP1 vs.AP2(P=0.011)showed a statistically significant difference.No significant difference was observed in the specificity between FDP(86.5%),AP1(92.3%)and AP2(89.4%)(P>0.05).FDP,AP1 and AP2 all showed high diagnostic performance,and the AUC were 0.899±0.025,0.866±0.029 and 0.930±0.021,respectively.The area under curve of AP1 was lower than that of FDP(P=0.014)and AP2(P=0.002),and there was no statistical difference between AP2 and FDP(P=0.116).Conclusion:AP of MRI can save medical resources and improve work efficiency,and the diagnostic efficiency of AP2 is comparable to that of FDP.AP2 has good clinical utility for breast cancer screening.
breast cancerbreast screeningmagnetic resonance imagingabbreviated protocol
万方数据
维普
