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颈部动脉夹层的长期超声随访观察

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目的:回顾性分析长期颈部动脉夹层(CeAD)患者的随访结果,探讨CeAD随时间的变化和影响其变化的相关因素.方法:本研究纳入了 2015 年至 2021 年收治的 113 例接受了抗血小板或抗凝治疗的成年CeAD患者.所有患者均进行了初始和多次随访血管超声检查,随访时间(4.7±5.5)个月,每位患者的临床和影像学数据均被记录.结果:113 例患者中发现了118 根夹层动脉,其中有63 例颈内动脉夹层(55.8%),45 例椎动脉夹层(39.8%),5 例患者(4.4%)中有多根动脉受到影响.1 例患者死亡(0.8%),84.1%的患者获得了相对较好的预后(mRS:0~1).50.9%的患者发病后的前 3 个月狭窄有所改善.应用改良的 Rankin 量表(mRS)、美国国立卫生研究院卒中量表(NIHSS)评估,颈内动脉夹层[NIHSS=2(0,4)分,mRS=1(0,2)分]与椎动脉夹层[NIHSS=0(0,1)分,mRS=0(0,0.5)分]相比有统计学意义(P<0.01).结论:CeAD的超声表现在发病后3 个月内高度动态变化,应仔细监测.一半以上的患者颈部动脉狭窄或闭塞程度在治疗后得到不同程度的改善或再通.颈内动脉夹层较椎动脉夹层发生更严重的神经功能损伤.
A long-term ultrasound follow-up observation of cervical artery dissection
Objective:This study aims to assess the long-term follow-up outcomes of patients with cervical artery dissection(CeAD),analyzing temporal changes in cervical artery dissection and identifving factors influencing these changes.Methods:The date of 113 adult patients with CeAD who received antiplatelet or anticoagulant therapy from 2015 to 2021.All patients underwent initial and multiple follow-up vascular ultrasound examinations,with a mean follow-up time of(4.7±5.5)months.Clinical and imaging data were recorded for each patient.Results:Among 113 patients,118 dissecting arteries were identified,comprising 63(55.8%)with internal carotid artery dissections,45(39.8%)with vertebral artery dissection,and 5(4.4%)with multiple affected arteries.One patient(0.8%)succumbed,while 84.1%of patients achieved a favorable prognosis(mRS:0~1).Within the first three months,50.9%of patients exhibited improved stenosis.The scores of Modified Rankin Scale(mRS),National Institute of Health Stroke Scale(NIHSS)were recorded.The scores of internal carotid artery dissections[NIHSS=2(0,4)points,mRS=1(0,2)points]showed statistically significant difference compared to vertebral artery dissection[NIHSS=0(0,1)points,mRS=0(0,0.5)points,P<0.01].Conclusion:Cervical artery dissection ultrasound findings exhibit high dynamic change in the initial three months,necessitating vigilant monitoring.Over half of patients with stenosis or occlusion witness varying degrees of improvement in arterial recanalization or stenosis severity after treament.Internal carotid artery dissection causes more severe neurological damage than vertebral artery dissection.

cervical artery dissectionultrasoundstrokefollow-up

张晋源、梁花敏、马薇、崔海鸥、王福霞、成江

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宁夏医科大学总医院 神经内科,宁夏 银川 750003

宁夏医科大学总医院 超声科,宁夏 银川 750003

颈部动脉夹层 超声 卒中 随访

宁夏回族自治区卫生健康系统科研项目宁夏医科大学校级重点项目

2021-NW-009XZ2021019

2024

暨南大学学报(自然科学与医学版)
暨南大学

暨南大学学报(自然科学与医学版)

CSTPCD北大核心
影响因子:0.996
ISSN:1000-9965
年,卷(期):2024.45(3)
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