Analysis of hospitalization expense and influencing factors for persistent pulmonary hypertension of the newborn in 37 hospitals in Guangdong province
Objective:To investigate the hospitalization expenses and contributing factors for neonate with persistent pulmonary hypertension of the newborn(PPHN)in 37 hospitals in Guangdong Province,providing insights for systematic management,healthcare communication,and policy-making in medical insurance.Methods:Medical records of PPHN neonates from 37 hospitals in Guangdong province(2015-2020)were collected.Hospitalization expense were analysed using descriptive statistics,and influential factors were determined through univariate analysis and recursive partitioning.Results:The average total hospitalization expense for PPHN neonates increased annually from 31 758(16 715,46 430)RMB in 2015 to 52 505(30 400,84 216)RMB in 2020.The total hospitalization cost of deceased children is 26 146(14 771,52 505)RMB,and the total hospitalization cost of surviving children is 44 245(21 274,74 197)RMB.Factors such as regional economic level(P<0.001),delivery methods(P<0.001),conception methods(P<0.001),gestational age(P<0.001),birth weight(P<0.001),gender(P=0.046),cause of PPHN(P<0.001),treatment with mechanical ventilation(P<0.001),use of pulmonary surfactant(PS)(P<0.001),inhaled nitric oxide(iNO)treatment(P<0.001),and duration of hospitalization(P<0.001)significantly influenced these expense.The recursive system model analysis shows that the influencing factors of hospitalization costs for children with PPHN,in descending order of total effect value,are:length of hospital stay,ventilator-associated ventilation,full-term infants,late preterm infants,use of iNO therapy,use of PS therapy,causative factors of pneumonia,delivery location,combination of two or more causative factors,and female birth gender.Conclusion:From 2015 to 2020,the hospitalization expense for patients with PPHN in Guangdong province increased due to various factors,with hospitalization duration being the predominant factor.Optimizing hospitalization length while ensuring medical quality and safety could effectively reduce PPHN-related hospitalization expense.