目的:通过流行病学调查研究胃癌前病变(precancerous lesions of gastric cancer,PLGC)患者湿证分布规律及相关影响因素.方法:收集2023年6月至2023年11月于广东省中医院就诊的PLGC患者流行病学资料,根据湿证类型进行分组,分析社会人口学资料、生活方式、疾病情况对不同湿证类型PLGC患者的影响,并对具有统计学差异的影响因素进行无序多分类Logistic回归分析.结果:本研究共收集到197例患者,其中非湿证35人、湿热证30人、脾湿证87人、风湿证17人、存在湿证兼夹者28人.对非湿证、湿热证、风湿证、脾湿证4组进行分析发现,其在是否忧郁、饮食习惯、食量、有无吸烟史、是否熬夜方面存在统计学差异,Logistic回归提示多忧郁、有吸烟史是湿热证的独立影响因素,熬夜是脾湿证的独立影响因素.结论:湿证广泛存在于PLGC患者中,多忧郁、有吸烟史可独立影响PLGC湿热证,熬夜可独立影响PLGC脾湿证.
Epidemiological investigation on the characteristics of dampness syndrome in patients with precancerous lesions of gastric cancer
Objective:To explore the distribution pattern and related influencing factors of dampness syndrome in patients with precancerous lesions of gastric cancer(PLGC)through epidemiological investigation.Methods:Epidemiological data of PLGC patients who visited Guangdong Provincial Hospital of Chinese Medicine from June 2023 to November 2023 were collected.After grouping them into different dampness syndrome types,analysed the effects of social demographics data,lifestyle,and disease conditions on PLGC patients with different dampness syndrome types.Finally,the influencing factors with statistical difference were analysed by unordered multiclassified Logistic regression analysis.Results:A total of 197 PLGC patients were collected in this study,including 35 patients with non-dampness syndrome,30 patients with dampness-heat syndrome,87 patients with spleen-dampness syndrome,17 patients with wind-dampness syndrome,and 28 patients with at least 2 different types of dampness syndrome.Correlation analysis of non-dampness syndrome group,dampness-heat syndrome group,spleen-dampness syndrome group,and wind-dampness syndrome group revealed that there were statistical differences among the four groups in depression,dietary habits,food intake,smoking history,and staying up late.Logistic regression analysis of the above factors revealed that depression and having smoking history were independent influencing factors of dampness-heat syndrome,and staying up late was an independent influencing factor of spleen-dampness syndrome.Conclusion:Dampness syndrome was widely present in PLGC patients,and depression and a history of smoking may independently affect dampness-heat syndrome in PLGC,while staying up late may independently affect spleen-dampness syndrome in PLGC.
precancerous lesions of gastric cancerdampness syndromeepidemiological investigationinfluencing factors
万方数据
维普
