Differential diagnosis of MSCT between lipid-poor renal angiomyolipoma and non-clean cell renal carcinoma
Objective To analyze the CT features of lipid-poor renal angiomyolipoma(AML)and non clear cell re-nal carcinoma,and to improve the differential diagnosis of the disease.Methods This retrospective study involved 19 cases of lipid-poor AML,16 cases of papillary renal cell carcinoma(PRCC),and 22 cases of chromophobe renal cell car-cinoma(ChRCC).The diagnosis of all cases was confirmed by surgery and pathology.The CT values in region of interest(ROI)were measured in both ipsilateral and contralateral kidneys in the plain scan phase,cortical phase,nephrogenic phase and excretory phase.The enhancement percentage,multiphase net increase and relative enhancement ratio were calculated and statistically analyzed.Results In the plain scan and cortical phase,the CT values of lipid-poor AML were higher than those of PRCC and ChRCC,and the differences were statistically significant(P<0.05).In the nephro-genic and excretory phases,there was no difference in CT values among the lipid-poor AML、PRCC and ChRCC.In the cortical phase,nephrogenic and excretory phases,the enhancement percentage of lipid-poor AML was higher than that of PRCC and ChRCC,and the differences were statistically significant(P<0.05).When comparing the lipid-poor AML and PRCC,the statistical differences of multiphase net increase and relative enhancement ratio were identified in both corti-comedullar and the nephrogenic phases.In the comparison of lipid-poor AML and ChRCC,the multiphase net increase and relative enhancement ratio demonstrated the statistical differences in both corticomedullar and the nephrogenic pha-ses(P<0.05).However,in the excretion phase,none of the above measurements showed statistical difference(P>0.05).Conclusion Lipid-poor AML,PRCC and ChRCC have specific CT features in the plain scan and enhanced scan phases.Adopting the enhancement percentage,multiphase net increase and relative enhancement ratio can further im-prove the differential diagnostic accuracy of AML from non-clean cell renal carcinoma.