Drug resistance is a huge challenge in the clinical treatment of non-small cell lung cancer,which is close-ly related to tumor recurrence and metastasis.Autophagy is an evolutionarily conserved metabolic process in eukaryotes.It maintains cell homeostasis by regulating organelles and protein degradation.Autophagy is tightly correlated with the de-velopment process and drug resistance of non-small cell lung cancer,and targeting autophagy-related genes of non-small cell lung cancer can affect drug sensitivity and alter the therapeutic effect of non-small cell lung culture.
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