Association study of non-enzyme antioxidant and lipid levels and anxiety and depressive symptoms in non-suicidal self-injury depressed patients
Objective To explore the correlation between non-enzymatic antioxidants and blood lipid levels and anxiety and depression symptoms in depressed patients with non-suicidal self-injury(NSSI).Methods Retrospectively,among 102 patients with depressive episode who were hospitalized in Wuhan Mental Health Center from September 2022 to September 2023,54 patients with depressive episode(NSSI group)and 48 patients with depressive episode without NSSI group(non-NSSI group)were selected as the research group and the control group respectively.Compare the levels of non-enzymatic antioxidants(TBiL,DBiL,ALB,UA),and blood lipid indexes(TC,TG,HDL-C,LDL-C)in adolescents with depression without NSSI behavior,to analyze the expression of non-enzymatic antioxidants and blood lipid indexes in NSSI depression patients;Associated analysis of non-enzymatic antioxidants(TBiL,DBiL,ALB,UA)and lipid indexes(TC,TG,HDL-C,LDL-C).Results Compared with the control group,serum TBIL,DBIL,UA in the study group were lower(P<0.05)and higher HDL-C(P<0.05).Family harmony(P=0.016,OR=6.925,95%CI:1.438-33.349)and depression lovel score(P<0.001,OR=1.215,95%CI:1.106-1.335)were independent risk factors for NSSI in adolescent depression.Conclusion Non-suicidal depressed patients may have oxidative stress and abnormal blood lipid levels,and harmonious family relationships and depressive symptoms are their independent risk factors.
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