Research progress in animal model construction of necrotizing fasciitis
Necrotizing fasciitis is a soft tissue infection that affects subcutaneous tissue,fascia,and muscles.It is characterized by widespread and rapid subcutaneous soft tissue infection,which can spread throughout the body in a short period of time.In severe cases,it can cause septic shock and multiple organ failure.In recent years,the incidence trend of necrotizing fasciitis has been increasing year by year,and the mortality rate and amputation rate of patients are also relatively high.The development of clinical diagnosis and treatment of necrotizing fasciitis is closely related to basic research.In order to increase our understanding of the pathogenesis of necrotizing fasciitis,a reliable animal model of necrotizing fasciitis is needed,which at least partially reflects the infection process of human necrotizing fasciitis.This article will briefly review the construction methods of animal models for necrotizing fasciitis,providing reference for research on the diagnosis and treatment of necrotizing fasciitis.
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